Effect of transcranial direct current stimulation combined with pelvic muscle training in women: Randomized, controlled, double‐blind, and clinical trial

• Published in: Neurourology and urodynamics 2024-04, Vol.43 (4), p.967-976
• Main Authors: Corrêa, Fernanda Ishida, Ledur, Ângela Cristina, Uehara, Laura, Andrade, Michele Lacerda, Corrêa, João Carlos Ferrari, Fregni, Felipe
• Format: Article
• Language: English
• Subjects: Electrical stimulation of the brain; Electroconvulsive therapy; ESB; Exercise Therapy; Female; Humans; intravaginal pressure; Muscle, Skeletal; Pelvic Floor; Pelvis; Quality of Life; strong muscle; Transcranial Direct Current Stimulation; Transcranial Direct Current Stimulation, health women; Treatment Outcome; Urinary Incontinence, Stress
• ISSN: 0733-2467; 1520-6777
• DOI: 10.1002/nau.25438

Background Pelvic floor muscle training (PFMT) is widely used for pelvic floor muscle (PFM) weakness in women; however, it has no prolonged effects. Objective To evaluate the effect of Transcranial Direct Current Stimulation (tDCS) associated with PFMT on PFM contraction, sexual function and quality of life (QoL) in healthy women. Study Design 32 nulliparous women, aged 22.7 ± 0.42 years, were randomized into two groups: G1 (active tDCS combined with PFMT) and G2 (sham tDCS combined with PFMT). The treatment was performed three times a week for 4 weeks, totaling 12 sessions. PFM function was assessed using the PERFECT scheme (P = power, E = endurance, R = repetitions, F = rapid contractions, ECT = each timed contraction) and the perineometer (cmH2O). Sexual function was assessed by The Female Sexual Function Index, and QoL by the SF‐36 questionnaire. These assessments were performed before and after the 12nd treatment session and after 30‐day follow‐up. Results There was a significant increase (p = 0.037) in the power of G2 compared to G1; repetitions and fast contraction increased in the G1 group, and the resistance increased in both groups, however, without statistical difference between the groups. ECT increased in the G1 group (p = 0.0). Conclusion Active tDCS combined with PFMT did not potentiate the effect of the PFMT to increase the PFM function, QoL, and sexual function in healthy women. However, adjunctive tDCS to PFMT improved the time of contractions, maintaining it during follow‐up.