A case report of aggressive mixed epithelial and stromal tumor of the kidney with malignant transformation

Mixed epithelial and stromal tumor of the kidney (MESTK) is a rare benign kidney tumor. In rare cases, malignant transformation, such as sarcomatoid features indicates poor clinical outcomes. In this study, we will describe a 45 years old man with a diagnosis of MESTK with malignant transformation o...

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Bibliographic Details
Published in:Urology case reports 2024, Vol.53, p.102689-102689
Main Authors: Ansari Djafari, Anahita, Rahnama, Hossein, Javanmard, Babak, Hojjati, Seyyed Ali, Salarinejad, Sareh
Format: Report
Language:English
Online Access:Get full text
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Summary:Mixed epithelial and stromal tumor of the kidney (MESTK) is a rare benign kidney tumor. In rare cases, malignant transformation, such as sarcomatoid features indicates poor clinical outcomes. In this study, we will describe a 45 years old man with a diagnosis of MESTK with malignant transformation of the sarcomatoid component, after right radical nephrectomy. The patient underwent chemotherapy with adriamycin, ifosfamide, and granulocyte-colony stimulating factor (G-CSF). The radiological characteristics of MESTK can pose diagnostic challenges due to its non-unique radiological appearance. The presence of sarcomatoid transformation is a hallmark feature of malignant MESTK which can be very aggressive.
ISSN:2214-4420
2214-4420
DOI:10.1016/j.eucr.2024.102689