Clinical outcomes of outpatient thyroidectomy: A systematic review and single-arm meta-analysis

• Published in: The American journal of surgery 2024-10, Vol.236, p.115694, Article 115694
• Main Authors: Nakanishi, Hayato, Wang, Rongzhi, Miangul, Shahid, Kim, Grace E., Segun-Omosehin, Omotayo A., Bourdakos, Natalie E., Than, Christian A., Johnson, Benjamin E., Chen, Herbert, Gillis, Andrea
• Format: Article
• Language: English
• Subjects: Adults; Ambulatory Surgical Procedures - adverse effects; Clinical trials; Cohort analysis; Complications; Criteria; Endocrine; Hematoma; Humans; Hypocalcemia; Medical personnel; Meta-analysis; Outpatient; Pathology; Patient satisfaction; Pediatrics; Postoperative; Postoperative Complications - epidemiology; Thyroid; Thyroid diseases; Thyroid gland; Thyroidectomy; Thyroidectomy - adverse effects; Thyroidectomy - methods; Treatment Outcome
• ISSN: 0002-9610; 1879-1883; 1879-1883
• DOI: 10.1016/j.amjsurg.2024.02.037

The aim of this meta-analysis is to investigate the safety of outpatient thyroidectomy based on 24-h and same-day discharge criteria. CENTRAL, Embase, PubMed, and Scopus were searched. A meta-analysis of selected studies was performed. The review was registered prospectively with PROSPERO (CRD42022361134). Thirty-one studies met the eligibility criteria, with a total of 74328 patients undergoing thyroidectomy in an outpatient setting based on 24-h discharge criteria. Overall postoperative complications after outpatient thyroidectomies were 5.7% (95%CI: 0.049–0.065; I2 ​= ​97.3%), consisting of hematoma (0.4%; 95%CI: 0.003–0.005; I2 ​= ​83.4%), recurrent laryngeal nerve injury (0.4%; 95%CI: 0.003–0.006; I2 ​= ​93.5%), and hypocalcemia (1.6%; 95%CI: 0.012–0.019; I2 ​= ​93.7%). The rate of readmission was 1.1% (95%CI: 0.007–0.015; I2 ​= ​95.4%). Results were similar for same-day criteria. Our analysis demonstrated that outpatient thyroidectomy is a safe procedure in the management of thyroid disease for selected patients. [Display omitted] •Outpatient thyroidectomy outcomes were analyzed from 24-h discharge criteria.•Our study demonstrated low overall and endocrine-related complication rates.•Low 30-day readmission, reoperation, and mortality rates were seen.•Similar results were observed based on same-day discharge criteria.•Outpatient thyroidectomy is a safe procedure for selected patients.