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Clinical outcomes of outpatient thyroidectomy: A systematic review and single-arm meta-analysis
The aim of this meta-analysis is to investigate the safety of outpatient thyroidectomy based on 24-h and same-day discharge criteria. CENTRAL, Embase, PubMed, and Scopus were searched. A meta-analysis of selected studies was performed. The review was registered prospectively with PROSPERO (CRD420223...
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Published in: | The American journal of surgery 2024-10, Vol.236, p.115694, Article 115694 |
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container_title | The American journal of surgery |
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creator | Nakanishi, Hayato Wang, Rongzhi Miangul, Shahid Kim, Grace E. Segun-Omosehin, Omotayo A. Bourdakos, Natalie E. Than, Christian A. Johnson, Benjamin E. Chen, Herbert Gillis, Andrea |
description | The aim of this meta-analysis is to investigate the safety of outpatient thyroidectomy based on 24-h and same-day discharge criteria.
CENTRAL, Embase, PubMed, and Scopus were searched. A meta-analysis of selected studies was performed. The review was registered prospectively with PROSPERO (CRD42022361134).
Thirty-one studies met the eligibility criteria, with a total of 74328 patients undergoing thyroidectomy in an outpatient setting based on 24-h discharge criteria. Overall postoperative complications after outpatient thyroidectomies were 5.7% (95%CI: 0.049–0.065; I2 = 97.3%), consisting of hematoma (0.4%; 95%CI: 0.003–0.005; I2 = 83.4%), recurrent laryngeal nerve injury (0.4%; 95%CI: 0.003–0.006; I2 = 93.5%), and hypocalcemia (1.6%; 95%CI: 0.012–0.019; I2 = 93.7%). The rate of readmission was 1.1% (95%CI: 0.007–0.015; I2 = 95.4%). Results were similar for same-day criteria.
Our analysis demonstrated that outpatient thyroidectomy is a safe procedure in the management of thyroid disease for selected patients.
[Display omitted]
•Outpatient thyroidectomy outcomes were analyzed from 24-h discharge criteria.•Our study demonstrated low overall and endocrine-related complication rates.•Low 30-day readmission, reoperation, and mortality rates were seen.•Similar results were observed based on same-day discharge criteria.•Outpatient thyroidectomy is a safe procedure for selected patients. |
doi_str_mv | 10.1016/j.amjsurg.2024.02.037 |
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CENTRAL, Embase, PubMed, and Scopus were searched. A meta-analysis of selected studies was performed. The review was registered prospectively with PROSPERO (CRD42022361134).
Thirty-one studies met the eligibility criteria, with a total of 74328 patients undergoing thyroidectomy in an outpatient setting based on 24-h discharge criteria. Overall postoperative complications after outpatient thyroidectomies were 5.7% (95%CI: 0.049–0.065; I2 = 97.3%), consisting of hematoma (0.4%; 95%CI: 0.003–0.005; I2 = 83.4%), recurrent laryngeal nerve injury (0.4%; 95%CI: 0.003–0.006; I2 = 93.5%), and hypocalcemia (1.6%; 95%CI: 0.012–0.019; I2 = 93.7%). The rate of readmission was 1.1% (95%CI: 0.007–0.015; I2 = 95.4%). Results were similar for same-day criteria.
Our analysis demonstrated that outpatient thyroidectomy is a safe procedure in the management of thyroid disease for selected patients.
[Display omitted]
•Outpatient thyroidectomy outcomes were analyzed from 24-h discharge criteria.•Our study demonstrated low overall and endocrine-related complication rates.•Low 30-day readmission, reoperation, and mortality rates were seen.•Similar results were observed based on same-day discharge criteria.•Outpatient thyroidectomy is a safe procedure for selected patients.</description><identifier>ISSN: 0002-9610</identifier><identifier>ISSN: 1879-1883</identifier><identifier>EISSN: 1879-1883</identifier><identifier>DOI: 10.1016/j.amjsurg.2024.02.037</identifier><identifier>PMID: 38443270</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adults ; Ambulatory Surgical Procedures - adverse effects ; Clinical trials ; Cohort analysis ; Complications ; Criteria ; Endocrine ; Hematoma ; Humans ; Hypocalcemia ; Medical personnel ; Meta-analysis ; Outpatient ; Pathology ; Patient satisfaction ; Pediatrics ; Postoperative ; Postoperative Complications - epidemiology ; Thyroid ; Thyroid diseases ; Thyroid gland ; Thyroidectomy ; Thyroidectomy - adverse effects ; Thyroidectomy - methods ; Treatment Outcome</subject><ispartof>The American journal of surgery, 2024-10, Vol.236, p.115694, Article 115694</ispartof><rights>2024</rights><rights>Copyright © 2024. Published by Elsevier Inc.</rights><rights>Copyright Elsevier Limited Oct 2024</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-7605140c54f24d50600bb8f60cb24526e00d9c201b78df5da7624f834f902fa83</citedby><cites>FETCH-LOGICAL-c393t-7605140c54f24d50600bb8f60cb24526e00d9c201b78df5da7624f834f902fa83</cites><orcidid>0000-0002-4481-5549 ; 0000-0002-2883-722X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38443270$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nakanishi, Hayato</creatorcontrib><creatorcontrib>Wang, Rongzhi</creatorcontrib><creatorcontrib>Miangul, Shahid</creatorcontrib><creatorcontrib>Kim, Grace E.</creatorcontrib><creatorcontrib>Segun-Omosehin, Omotayo A.</creatorcontrib><creatorcontrib>Bourdakos, Natalie E.</creatorcontrib><creatorcontrib>Than, Christian A.</creatorcontrib><creatorcontrib>Johnson, Benjamin E.</creatorcontrib><creatorcontrib>Chen, Herbert</creatorcontrib><creatorcontrib>Gillis, Andrea</creatorcontrib><title>Clinical outcomes of outpatient thyroidectomy: A systematic review and single-arm meta-analysis</title><title>The American journal of surgery</title><addtitle>Am J Surg</addtitle><description>The aim of this meta-analysis is to investigate the safety of outpatient thyroidectomy based on 24-h and same-day discharge criteria.
CENTRAL, Embase, PubMed, and Scopus were searched. A meta-analysis of selected studies was performed. The review was registered prospectively with PROSPERO (CRD42022361134).
Thirty-one studies met the eligibility criteria, with a total of 74328 patients undergoing thyroidectomy in an outpatient setting based on 24-h discharge criteria. Overall postoperative complications after outpatient thyroidectomies were 5.7% (95%CI: 0.049–0.065; I2 = 97.3%), consisting of hematoma (0.4%; 95%CI: 0.003–0.005; I2 = 83.4%), recurrent laryngeal nerve injury (0.4%; 95%CI: 0.003–0.006; I2 = 93.5%), and hypocalcemia (1.6%; 95%CI: 0.012–0.019; I2 = 93.7%). The rate of readmission was 1.1% (95%CI: 0.007–0.015; I2 = 95.4%). Results were similar for same-day criteria.
Our analysis demonstrated that outpatient thyroidectomy is a safe procedure in the management of thyroid disease for selected patients.
[Display omitted]
•Outpatient thyroidectomy outcomes were analyzed from 24-h discharge criteria.•Our study demonstrated low overall and endocrine-related complication rates.•Low 30-day readmission, reoperation, and mortality rates were seen.•Similar results were observed based on same-day discharge criteria.•Outpatient thyroidectomy is a safe procedure for selected patients.</description><subject>Adults</subject><subject>Ambulatory Surgical Procedures - adverse effects</subject><subject>Clinical trials</subject><subject>Cohort analysis</subject><subject>Complications</subject><subject>Criteria</subject><subject>Endocrine</subject><subject>Hematoma</subject><subject>Humans</subject><subject>Hypocalcemia</subject><subject>Medical personnel</subject><subject>Meta-analysis</subject><subject>Outpatient</subject><subject>Pathology</subject><subject>Patient satisfaction</subject><subject>Pediatrics</subject><subject>Postoperative</subject><subject>Postoperative Complications - epidemiology</subject><subject>Thyroid</subject><subject>Thyroid diseases</subject><subject>Thyroid gland</subject><subject>Thyroidectomy</subject><subject>Thyroidectomy - adverse effects</subject><subject>Thyroidectomy - methods</subject><subject>Treatment Outcome</subject><issn>0002-9610</issn><issn>1879-1883</issn><issn>1879-1883</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNqFkUtv1DAURi0EotPCTwBFYsMm6fUjicMGVSMelSqxadeW40dxFMeD7RTl3-NhBhZsWPla99xr63wIvcHQYMDd9dRIP6U1PjYECGuANED7Z2iHeT_UmHP6HO0AgNRDh-ECXaY0lSvGjL5EF5QzRkkPOyT2s1ucknMV1qyCN6kK9lgfZHZmyVX-vsXgtFE5-O1DdVOlLWXjS1dV0Tw587OSi66SWx5nU8voK2-yrOUi5y259Aq9sHJO5vX5vEIPnz_d77_Wd9--3O5v7mpFB5rrvoMWM1Ats4TpFjqAceS2AzUS1pLOAOhBEcBjz7Vttew7wiynzA5ArOT0Cr0_7T3E8GM1KQvvkjLzLBcT1iTIQDnhLXBa0Hf_oFNYY_lvEhQD6TFpf1PtiVIxpBSNFYfovIybwCCOCYhJnBMQxwQEEFESKHNvz9vX0Rv9d-qP8gJ8PAGm6Cj-okiqmFZGu1gsCx3cf574BYznmbk</recordid><startdate>20241001</startdate><enddate>20241001</enddate><creator>Nakanishi, Hayato</creator><creator>Wang, Rongzhi</creator><creator>Miangul, Shahid</creator><creator>Kim, Grace E.</creator><creator>Segun-Omosehin, Omotayo A.</creator><creator>Bourdakos, Natalie E.</creator><creator>Than, Christian A.</creator><creator>Johnson, Benjamin E.</creator><creator>Chen, Herbert</creator><creator>Gillis, Andrea</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-4481-5549</orcidid><orcidid>https://orcid.org/0000-0002-2883-722X</orcidid></search><sort><creationdate>20241001</creationdate><title>Clinical outcomes of outpatient thyroidectomy: A systematic review and single-arm meta-analysis</title><author>Nakanishi, Hayato ; 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CENTRAL, Embase, PubMed, and Scopus were searched. A meta-analysis of selected studies was performed. The review was registered prospectively with PROSPERO (CRD42022361134).
Thirty-one studies met the eligibility criteria, with a total of 74328 patients undergoing thyroidectomy in an outpatient setting based on 24-h discharge criteria. Overall postoperative complications after outpatient thyroidectomies were 5.7% (95%CI: 0.049–0.065; I2 = 97.3%), consisting of hematoma (0.4%; 95%CI: 0.003–0.005; I2 = 83.4%), recurrent laryngeal nerve injury (0.4%; 95%CI: 0.003–0.006; I2 = 93.5%), and hypocalcemia (1.6%; 95%CI: 0.012–0.019; I2 = 93.7%). The rate of readmission was 1.1% (95%CI: 0.007–0.015; I2 = 95.4%). Results were similar for same-day criteria.
Our analysis demonstrated that outpatient thyroidectomy is a safe procedure in the management of thyroid disease for selected patients.
[Display omitted]
•Outpatient thyroidectomy outcomes were analyzed from 24-h discharge criteria.•Our study demonstrated low overall and endocrine-related complication rates.•Low 30-day readmission, reoperation, and mortality rates were seen.•Similar results were observed based on same-day discharge criteria.•Outpatient thyroidectomy is a safe procedure for selected patients.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>38443270</pmid><doi>10.1016/j.amjsurg.2024.02.037</doi><orcidid>https://orcid.org/0000-0002-4481-5549</orcidid><orcidid>https://orcid.org/0000-0002-2883-722X</orcidid></addata></record> |
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subjects | Adults Ambulatory Surgical Procedures - adverse effects Clinical trials Cohort analysis Complications Criteria Endocrine Hematoma Humans Hypocalcemia Medical personnel Meta-analysis Outpatient Pathology Patient satisfaction Pediatrics Postoperative Postoperative Complications - epidemiology Thyroid Thyroid diseases Thyroid gland Thyroidectomy Thyroidectomy - adverse effects Thyroidectomy - methods Treatment Outcome |
title | Clinical outcomes of outpatient thyroidectomy: A systematic review and single-arm meta-analysis |
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