Polymeric coatings for biomedical devices

• Published in: Surface science 2004-10, Vol.570 (1), p.111-118
• Main Authors: Murata, H., Chang, B.-J., Prucker, O., Dahm, M., Rühe, J.
• Format: Article
• Language: English
• Subjects: Biological compounds; Coatings; Condensed matter: electronic structure, electrical, magnetic, and optical properties; Condensed matter: structure, mechanical and thermal properties; Cross-disciplinary physics: materials science; rheology; Exact sciences and technology; Glass surfaces; Photochemistry; Physics; Self-assembly
• ISSN: 0039-6028; 1879-2758
• DOI: 10.1016/j.susc.2004.06.185

To improve the properties of materials in biomedical applications and to allow a better interaction of the medical device with the biological system surrounding it, frequently polymeric coatings are applied. However, the adhesion of the coating to the substrate usually poses a problem as the materials involved have either rather inert surfaces or strongly varying surface chemistries. We describe a new approach which allows to attach a wide variety of polymer films to organic substrates either of polymeric or biological origin. The technique is based on photochemical processes occurring in benzophenone group containing polymers, which lead to simultaneous crosslinking of the polymer in the coating and surface-attachment of the forming polymer network. The synthesis and characterization of monolayers and surface-attached polymer networks through this route are described and possible applications of this approach in the biomedical area are discussed.