Combining Fluorescent Probes and Biofunctional Magnetic Nanoparticles for Rapid Detection of Bacteria in Human Blood

Detection of bacteria in human blood within two hours is achieved through the use of vancomycin‐functionalized FePt nanoparticles in combination with a vancomycin‐conjugated fluorescent probe, as shown in the figure (B: bacteria; Van: vancomycin; FLA: fluorescein amine). This promises to be a sensit...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2006-12, Vol.18 (23), p.3145-3148
Main Authors: Gao, J., Li, L., Ho, P.-L., Mak, G. C., Gu, H., Xu, B.
Format: Article
Language:English
Subjects:
Bacteria
Biomedical applications
Biomedical applications, magnetic
Biosensors
Fluorescence imaging
magnetic
Nanoparticles
Nanoparticles, magnetic
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Summary:Detection of bacteria in human blood within two hours is achieved through the use of vancomycin‐functionalized FePt nanoparticles in combination with a vancomycin‐conjugated fluorescent probe, as shown in the figure (B: bacteria; Van: vancomycin; FLA: fluorescein amine). This promises to be a sensitive and rapid protocol for detecting bacteria in blood products or other targets in biological samples.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200601058