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Predictive value of the Global Activity Limitation Indicator (GALI) on all-cause mortality
The Global Activity Limitation Indicator (GALI) is an instrument that measures long-term overall disability. The objective of this study was to evaluate GALI's predictive value on mortality while examining variations according to sex, age, and educational level. Longitudinal study. This longitu...
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Published in: | Public health (London) 2024-05, Vol.230, p.6-11 |
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description | The Global Activity Limitation Indicator (GALI) is an instrument that measures long-term overall disability. The objective of this study was to evaluate GALI's predictive value on mortality while examining variations according to sex, age, and educational level.
Longitudinal study.
This longitudinal study was based on 42,991 individuals aged ≥15 years who participated in the 2011–2012 National Health Survey and the 2014 European Health Survey in Spain. These records were linked to mortality data up to December 2021. GALI assessed self-reported functional limitation in the past 6 months and classified individuals into three categories: severely limited, limited but not severely, and not limited. Incidence rate ratios (IRR) were calculated using Poisson regression models, adjusting for sociodemographic, lifestyle, and health status variables.
Compared to individuals with no limitations, those with non-severe limitations had an IRR for mortality of 1.27 (95% CI: 1.16–1.38), and 2.04 (95% CI: 1.81–2.31) in those with severe limitations. Women with severe limitations exhibited a higher IRR (2.32; 95% CI: 1.98–2.71) compared to men (1.73; 95% CI: 1.45–2.08) (P for interaction = 0.005). Individuals |
doi_str_mv | 10.1016/j.puhe.2024.02.006 |
format | article |
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Longitudinal study.
This longitudinal study was based on 42,991 individuals aged ≥15 years who participated in the 2011–2012 National Health Survey and the 2014 European Health Survey in Spain. These records were linked to mortality data up to December 2021. GALI assessed self-reported functional limitation in the past 6 months and classified individuals into three categories: severely limited, limited but not severely, and not limited. Incidence rate ratios (IRR) were calculated using Poisson regression models, adjusting for sociodemographic, lifestyle, and health status variables.
Compared to individuals with no limitations, those with non-severe limitations had an IRR for mortality of 1.27 (95% CI: 1.16–1.38), and 2.04 (95% CI: 1.81–2.31) in those with severe limitations. Women with severe limitations exhibited a higher IRR (2.32; 95% CI: 1.98–2.71) compared to men (1.73; 95% CI: 1.45–2.08) (P for interaction = 0.005). Individuals <65 years with severe limitations showed a greater association (2.22; 95% CI: 1.58–3.10) than those ≥65 (1.49; 95% CI: 1.32–1.69) (P for interaction <0.001). Among individuals with lower educational attainment, the IRR was 2.08 (95% CI: 1.83–2.37), and 1.87 (95% CI: 1.37–2.56) for the higher education group (P for interaction = 0.017).
GALI is a robust predictor of all-cause mortality in the general population and subgroups. The association is stronger in women, individuals <65 years, and those with lower educational levels.</description><identifier>ISSN: 0033-3506</identifier><identifier>EISSN: 1476-5616</identifier><identifier>DOI: 10.1016/j.puhe.2024.02.006</identifier><identifier>PMID: 38460397</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Disability ; Disabled Persons ; Female ; GALI ; Health Status ; Health Status Indicators ; Health Surveys ; Humans ; Longitudinal Studies ; Male ; Mortality</subject><ispartof>Public health (London), 2024-05, Vol.230, p.6-11</ispartof><rights>2024 The Royal Society for Public Health</rights><rights>Copyright © 2024 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c307t-5c279f45187c57c0714ed5aee6c4d25c215114e79ff8ee270debab986b5c62dc3</cites><orcidid>0000-0003-3829-0675 ; 0000-0003-0624-9993 ; 0000-0002-6731-0412 ; 0000-0002-5542-9782</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38460397$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ayuso-Álvarez, A.</creatorcontrib><creatorcontrib>Ortiz, C.</creatorcontrib><creatorcontrib>Fontán, J.</creatorcontrib><creatorcontrib>Rodríguez-Blázquez, C.</creatorcontrib><creatorcontrib>Damián, J.</creatorcontrib><creatorcontrib>López-Cuadrado, T.</creatorcontrib><creatorcontrib>Galán, I.</creatorcontrib><title>Predictive value of the Global Activity Limitation Indicator (GALI) on all-cause mortality</title><title>Public health (London)</title><addtitle>Public Health</addtitle><description>The Global Activity Limitation Indicator (GALI) is an instrument that measures long-term overall disability. The objective of this study was to evaluate GALI's predictive value on mortality while examining variations according to sex, age, and educational level.
Longitudinal study.
This longitudinal study was based on 42,991 individuals aged ≥15 years who participated in the 2011–2012 National Health Survey and the 2014 European Health Survey in Spain. These records were linked to mortality data up to December 2021. GALI assessed self-reported functional limitation in the past 6 months and classified individuals into three categories: severely limited, limited but not severely, and not limited. Incidence rate ratios (IRR) were calculated using Poisson regression models, adjusting for sociodemographic, lifestyle, and health status variables.
Compared to individuals with no limitations, those with non-severe limitations had an IRR for mortality of 1.27 (95% CI: 1.16–1.38), and 2.04 (95% CI: 1.81–2.31) in those with severe limitations. Women with severe limitations exhibited a higher IRR (2.32; 95% CI: 1.98–2.71) compared to men (1.73; 95% CI: 1.45–2.08) (P for interaction = 0.005). Individuals <65 years with severe limitations showed a greater association (2.22; 95% CI: 1.58–3.10) than those ≥65 (1.49; 95% CI: 1.32–1.69) (P for interaction <0.001). Among individuals with lower educational attainment, the IRR was 2.08 (95% CI: 1.83–2.37), and 1.87 (95% CI: 1.37–2.56) for the higher education group (P for interaction = 0.017).
GALI is a robust predictor of all-cause mortality in the general population and subgroups. The association is stronger in women, individuals <65 years, and those with lower educational levels.</description><subject>Disability</subject><subject>Disabled Persons</subject><subject>Female</subject><subject>GALI</subject><subject>Health Status</subject><subject>Health Status Indicators</subject><subject>Health Surveys</subject><subject>Humans</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Mortality</subject><issn>0033-3506</issn><issn>1476-5616</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9kMFqGzEQhkVJaZy0L9BD0TE97HakXUlryMWE1DUYmkN66UVotbNERms5ktaQt6-Mkxx7Gpj5_h_mI-Qrg5oBkz929WF-wpoDb2vgNYD8QBasVbISkskLsgBomqoRIC_JVUo7AOCqEZ_IZdO1EpqlWpC_DxEHZ7M7Ij0aPyMNI81PSNc-9MbT1enk8gvdusllk13Y082-JEwOkd6sV9vNd1p2xvvKmjkhnULMxpfIZ_JxND7hl9d5Tf78vH-8-1Vtf683d6ttZRtQuRKWq-XYCtYpK5QFxVochEGUth14uTLByqowY4fIFQzYm37ZyV5YyQfbXJObc-8hhucZU9aTSxa9N3sMc9J8KVqleAddQfkZtTGkFHHUh-gmE180A31yqnf65FSfnGrgujgtoW-v_XM_4fAeeZNYgNszgOXLo8Ook3W4t0VsRJv1ENz_-v8BpCKH4g</recordid><startdate>202405</startdate><enddate>202405</enddate><creator>Ayuso-Álvarez, A.</creator><creator>Ortiz, C.</creator><creator>Fontán, J.</creator><creator>Rodríguez-Blázquez, C.</creator><creator>Damián, J.</creator><creator>López-Cuadrado, T.</creator><creator>Galán, I.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-3829-0675</orcidid><orcidid>https://orcid.org/0000-0003-0624-9993</orcidid><orcidid>https://orcid.org/0000-0002-6731-0412</orcidid><orcidid>https://orcid.org/0000-0002-5542-9782</orcidid></search><sort><creationdate>202405</creationdate><title>Predictive value of the Global Activity Limitation Indicator (GALI) on all-cause mortality</title><author>Ayuso-Álvarez, A. ; Ortiz, C. ; Fontán, J. ; Rodríguez-Blázquez, C. ; Damián, J. ; López-Cuadrado, T. ; Galán, I.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c307t-5c279f45187c57c0714ed5aee6c4d25c215114e79ff8ee270debab986b5c62dc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Disability</topic><topic>Disabled Persons</topic><topic>Female</topic><topic>GALI</topic><topic>Health Status</topic><topic>Health Status Indicators</topic><topic>Health Surveys</topic><topic>Humans</topic><topic>Longitudinal Studies</topic><topic>Male</topic><topic>Mortality</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ayuso-Álvarez, A.</creatorcontrib><creatorcontrib>Ortiz, C.</creatorcontrib><creatorcontrib>Fontán, J.</creatorcontrib><creatorcontrib>Rodríguez-Blázquez, C.</creatorcontrib><creatorcontrib>Damián, J.</creatorcontrib><creatorcontrib>López-Cuadrado, T.</creatorcontrib><creatorcontrib>Galán, I.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Public health (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ayuso-Álvarez, A.</au><au>Ortiz, C.</au><au>Fontán, J.</au><au>Rodríguez-Blázquez, C.</au><au>Damián, J.</au><au>López-Cuadrado, T.</au><au>Galán, I.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predictive value of the Global Activity Limitation Indicator (GALI) on all-cause mortality</atitle><jtitle>Public health (London)</jtitle><addtitle>Public Health</addtitle><date>2024-05</date><risdate>2024</risdate><volume>230</volume><spage>6</spage><epage>11</epage><pages>6-11</pages><issn>0033-3506</issn><eissn>1476-5616</eissn><abstract>The Global Activity Limitation Indicator (GALI) is an instrument that measures long-term overall disability. The objective of this study was to evaluate GALI's predictive value on mortality while examining variations according to sex, age, and educational level.
Longitudinal study.
This longitudinal study was based on 42,991 individuals aged ≥15 years who participated in the 2011–2012 National Health Survey and the 2014 European Health Survey in Spain. These records were linked to mortality data up to December 2021. GALI assessed self-reported functional limitation in the past 6 months and classified individuals into three categories: severely limited, limited but not severely, and not limited. Incidence rate ratios (IRR) were calculated using Poisson regression models, adjusting for sociodemographic, lifestyle, and health status variables.
Compared to individuals with no limitations, those with non-severe limitations had an IRR for mortality of 1.27 (95% CI: 1.16–1.38), and 2.04 (95% CI: 1.81–2.31) in those with severe limitations. Women with severe limitations exhibited a higher IRR (2.32; 95% CI: 1.98–2.71) compared to men (1.73; 95% CI: 1.45–2.08) (P for interaction = 0.005). Individuals <65 years with severe limitations showed a greater association (2.22; 95% CI: 1.58–3.10) than those ≥65 (1.49; 95% CI: 1.32–1.69) (P for interaction <0.001). Among individuals with lower educational attainment, the IRR was 2.08 (95% CI: 1.83–2.37), and 1.87 (95% CI: 1.37–2.56) for the higher education group (P for interaction = 0.017).
GALI is a robust predictor of all-cause mortality in the general population and subgroups. The association is stronger in women, individuals <65 years, and those with lower educational levels.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>38460397</pmid><doi>10.1016/j.puhe.2024.02.006</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0003-3829-0675</orcidid><orcidid>https://orcid.org/0000-0003-0624-9993</orcidid><orcidid>https://orcid.org/0000-0002-6731-0412</orcidid><orcidid>https://orcid.org/0000-0002-5542-9782</orcidid></addata></record> |
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subjects | Disability Disabled Persons Female GALI Health Status Health Status Indicators Health Surveys Humans Longitudinal Studies Male Mortality |
title | Predictive value of the Global Activity Limitation Indicator (GALI) on all-cause mortality |
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