The Conversion and Degradation of Sulphaguanidine under UV and Electron Beam Irradiation Using Fluorescence

• Published in: Journal of fluorescence 2024-03
• Main Authors: Bezlepkina, Nadezhda P, Bocharnikova, Elena N, Tchaikovskaya, Olga N, Mayer, Georgy V, Solomonov, Vladimir I, Makarova, Anna S, Spirina, Alya V, Chaikovsky, Stanislav A
• Format: Article
• Language: English
• ISSN: 1053-0509; 1573-4994
• DOI: 10.1007/s10895-024-03640-w

The work presents a spectral-luminescent study of the sulfaguanidine transformation in water under a pulsed e-beam and UV irradiation of an UVb-04 bactericidal mercury lamp (from 180 to 275 nm), KrCl (222 nm), XeBr (282 nm) and XeCl (308 nm) excilamps. Fluorescent decay curves have been used in our analysis of the sulfaguanidine decomposition. The conversion of antibiotic under e-beam irradiation for up to 1 min was more than 80%, compared with UV radiation: UVb-04-26%, XeBr - 20%. KrCl and XeCl - about 10%. At the end of 64 min of irradiation with UVb-04 and XeBr lamps, the conversion was 99%. During irradiation with these lamps, sulfaguanidine almost completely decomposed and passed into the final fluorescent photoproducts. After e-beam irradiated at the end of 13 min the decrease in sulfaguanidine was 93%. At the same time, the formation of sulfaguanidine transformation products was minimal compared to UV irradiation. The effect of UV irradiation and a powerful e-beam on the decomposition mechanisms of sulfaguanidine are significantly different, which is manifested in various changes in the absorption and fluorescence spectra.