Kidney transplantation in prostate cancer patients after local therapy with curative intent: a systematic review

Purpose It is still unclear whether kidney transplantation can be safely performed in patients with prostate cancer after local therapy with curative intent. Methods The protocol was registered in PROSPERO. We systematically searched Google, MEDLINE, the Cochrane Library, and the ICTRP for studies,...

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Bibliographic Details
Published in:World journal of urology 2024-03, Vol.42 (1), p.127, Article 127
Main Authors: Rumpff, C., Lieb, V., Wullich, B., Schiffer, M., Kunath, F., Apel, H.
Format: Article
Language:English
Subjects:
Cancer therapies
Clinical medicine
Clinical practice guidelines
Humans
Kidney transplantation
Kidney Transplantation - adverse effects
Kidney transplants
Male
Medicine
Medicine & Public Health
Nephrology
Oncology
Patients
Prostate cancer
Prostatic Neoplasms - etiology
Prostatic Neoplasms - surgery
Retrospective Studies
Topic Paper
Urology
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Summary:Purpose It is still unclear whether kidney transplantation can be safely performed in patients with prostate cancer after local therapy with curative intent. Methods The protocol was registered in PROSPERO. We systematically searched Google, MEDLINE, the Cochrane Library, and the ICTRP for studies, official standards, clinical practice guidelines and organ transplant laws. Two review authors independently examined the full-text reports and identified relevant studies and one review author extracted the data. We assessed the overall certainty of the evidence for each outcome according to the GRADE approach. Results We identified 1346 references through electronic database searching and finally included 6 references for official standards, clinical practice guidelines, and organ transplant laws, and 6 references for retrospective studies with very low certainty of evidence. We identified no prospective or ongoing studies and reported all results narratively. Conclusion We recommend that decisions on kidney transplantation in patients with prostate cancer after local therapy with curative intent should be made on a case-by-case basis. It is indispensable to consult with health care professionals or specialists at transplant centers to obtain individualized information regarding the waiting time requirements for renal transplantation in prostate cancer patients after local therapy with curative intent. No recommendation can be made regarding the waiting times after prostate cancer therapy with curative intent.
ISSN:1433-8726
0724-4983
1433-8726
DOI:10.1007/s00345-024-04817-5