Optical Coherence Tomography Angiography in Vogt-Koyanagi-Harada Patients: A Systematic Review and Meta-Analysis

To describe the choroidal retinal microvascular system in Vogt-Koyanagi-Harada (VKH) subjects and furnish additional proof for the early authentication and treatment of VKH suffers. From the beginning to July 2023, a comprehensive search for issued articles on optical coherence tomography angiograph...

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Bibliographic Details
Published in:Current eye research 2024-09, Vol.49 (9), p.1-904
Main Authors: Liang, Ruyu, Geng, Jiawei, Jiang, Hai, Jin, Siyan, Wang, Xia, Liu, Xiaoli
Format: Article
Language:English
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Summary:To describe the choroidal retinal microvascular system in Vogt-Koyanagi-Harada (VKH) subjects and furnish additional proof for the early authentication and treatment of VKH suffers. From the beginning to July 2023, a comprehensive search for issued articles on optical coherence tomography angiography (OCTA) among VKH sufferers was implemented in Embase, PubMed, and Web of Science databases. This meta-analysis included 9 eligible studies. Primary endpoints included four kinds of vascular densities, such as superficial capillaris plexus (SCP), deep capillaris plexus (DCP), and choriocapillary (CC). In addition to these, there were foveal avascular zone (FAZ), central retinal thickness (CT), best-corrected distance visual acuity (BCVA log MAR), and subfoveal choroidal thickness (SFCT). SCP and DCP vessel densities in maculas were both smaller in VKH sufferers in the active stage than those normal and remission examinees (SCP vessel density,  
ISSN:0271-3683
1460-2202
1460-2202
DOI:10.1080/02713683.2024.2327054