Beyond the cradle – Amidst microplastics and the ongoing peril during pregnancy and neonatal stages: A holistic review

• Published in: Journal of hazardous materials 2024-05, Vol.469, p.133963, Article 133963
• Main Authors: Paul, Indrani, Mondal, Pritam, Haldar, Dibyajyoti, Halder, Gopinath
• Format: Article
• Language: English
• Subjects: Awareness; Microplastic; Mitigation; Neonates; Pregnancy
• ISSN: 0304-3894; 1873-3336; 1873-3336
• DOI: 10.1016/j.jhazmat.2024.133963

Advancements in research concerning the occurrence of microplastics (MPs) in human blood, sputum, urine, and breast milk samples have piqued the interest of the scientific community, prompting further investigation. MPs present in the placenta, amniotic fluid, and meconium raise concerns about interference with embryonic development, leading to preeclampsia, stillbirth, preterm birth, and spontaneous abortion. The challenges posed by MPs extend beyond pregnancy, affecting the digestive, reproductive, circulatory, immune, and central nervous systems. This has spurred scientists to examine the origins of MPs in distinct environmental layers, including air, water, and soil. These risks continue after birth, as neonates are continuously exposed to MPs through everyday items such as breast milk, cow milk and infant milk powder, as well as plastic-based products like feeding bottles and breast milk storage bags. It is the need of the hour to strike a balance amidst lifestyle changes, alternative choices to traditional plastic products, raising awareness about plastic-related health risks, and fostering collaboration between the scientific community and policymakers. This review aims to provide fresh insights into potential sources of MP pollution, with a specific focus on pregnancy and neonates. It is the first compilation of its kind so far that includes critical studies on recently reported discoveries. [Display omitted] •Deleterious impacts of microplastics (MPs) on pregnant women and neonates.•Identifying sources of MPs during critical stages of gestation.•Routes and risks of MP contaminations during fetal development.•Detection of MP exposure during vulnerable neonatal stages.•Control and mitigation of MPs in developing embryo and newborns.