Instrumental—analytical method for estimation of health state of the body and its systems after exposure to radiation

• Published in: Biomedical engineering 2006-05, Vol.40 (3), p.113-116
• Main Authors: Stavitskii, R V, Lebedev, L A, Vasil'ev, V N, Mikheechev, A V, Mikheenko, S G, Yan, A M, Barkhudarov, R M, Kravchenko, M V, Lobov, D P, Ivanova, V V, Lobova, E N
• Format: Article
• Language: English
• Subjects: Estimating techniques; Health risk assessment; Human exposure; Radiation; Radiation effects
• ISSN: 0006-3398; 1573-8256
• DOI: 10.1007/s10527-006-0056-0

Changes in the human body state and functions induced by exposure to relatively high doses of ionizing radiation (>100 mSv) can be easily detected using biological methods: monitoring of the number and type of chromosomal aberrations, analysis of tooth enamel, detection of functional changes of individual organs and systems. It is virtually impossible to detect nonspecific nonmalignant diseases under conditions of exposure to relatively low doses of ionizing radiation. In this case, no statistically significant correlation between radiation dose and effects induced by the radiation in any organ or tissue can be found, even if the sample size is rather large. This can be attributed to the following factors: broad variability of the sensitivity of the whole body and its systems to low doses of ionizing radiation; recovery processes most pronounced under conditions of exposure to relatively low doses of ionizing radia tion; age and, perhaps, gender instability in body reaction to relatively low doses of ionizing radiation.