Unlocking the mystery of the feeder organelle and versatile energy metabolism in Cryptosporidium parvum

Xu and colleagues recently revealed the critical role of Cryptosporidium's feeder organelle in nutrient uptake, showcasing the parasite's ability to harness glucose and glucose-6-phosphate from host cells. This illuminates the sophisticated energy metabolism and survival strategies of the...

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Bibliographic Details
Published in:Trends in parasitology 2024-04, Vol.40 (4), p.280-282
Main Authors: Wang, Dongqiang, Zhu, Guan
Format: Article
Language:English
Subjects:
aldolase
Cryptosporidium parvum
feeder organelle
glucose transporters
glycogen phosphorylase
hexokinase
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Summary:Xu and colleagues recently revealed the critical role of Cryptosporidium's feeder organelle in nutrient uptake, showcasing the parasite's ability to harness glucose and glucose-6-phosphate from host cells. This illuminates the sophisticated energy metabolism and survival strategies of the parasite, highlighting potential therapeutic targets. Xu and colleagues recently revealed the critical role of Cryptosporidium's feeder organelle in nutrient uptake, showcasing the parasite's ability to harness glucose and glucose-6-phosphate from host cells. This illuminates the sophisticated energy metabolism and survival strategies of the parasite, highlighting potential therapeutic targets.
ISSN:1471-4922
1471-5007
DOI:10.1016/j.pt.2024.03.002