Using a Core-Sheath Distribution of Surface Chemistry through 3D Tissue Engineering Scaffolds to Control Cell Ingress

A core/sheath distribution of cell‐adhesive and non‐cell‐adhesive surface coatings is produced in porous biodegradable poly(D,L‐lactic acid) discs using sequential plasma polymerization. The figure and cover show an X‐ray micro‐computed tomography image of a section of a 10 mm diameter, 4 mm thick s...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2006-06, Vol.18 (11), p.1406-1410
Main Authors: Barry, J. J. A., Howard, D., Shakesheff, K. M., Howdle, S. M., Alexander, M. R.
Format: Article
Language:English
Subjects:
Cells
plasma
Polymerization
Polymerization, plasma
Surface modification
Tissue engineering
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Summary:A core/sheath distribution of cell‐adhesive and non‐cell‐adhesive surface coatings is produced in porous biodegradable poly(D,L‐lactic acid) discs using sequential plasma polymerization. The figure and cover show an X‐ray micro‐computed tomography image of a section of a 10 mm diameter, 4 mm thick scaffold where fibroblast cells (shown in red) have been encouraged by the surface chemistry to penetrate to the scaffold core.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200502719