Familial Deep Vein Thrombosis in a Child With Antithrombin III Deficiency: A Case Report

Deep vein thrombosis (DVT) is caused by a clot (thrombus) formed in the deep veins, usually the legs. The incidence of DVT is notably less prevalent in children than in adults. Here, we present a rare case of DVT in an eight-year-old female child with a significant family history involving the untim...

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Bibliographic Details
Published in:Cureus 2024, Vol.16 (2), p.e54157-e54157
Main Authors: Kale, Shivani, Jadhav, Devika, Tambolkar, Sampada, Daru, Avinash
Format: Report
Language:English
Online Access:Get full text
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Summary:Deep vein thrombosis (DVT) is caused by a clot (thrombus) formed in the deep veins, usually the legs. The incidence of DVT is notably less prevalent in children than in adults. Here, we present a rare case of DVT in an eight-year-old female child with a significant family history involving the untimely death of the maternal aunt. The child presented with pain and edema in the left lower limb causing immobilization without any obvious cause. The clinical features suggested the possibility of DVT. On further evaluation and radiological investigations, the diagnosis of DVT was confirmed. A complete thrombophilia workup was done showing antithrombin (AT) III deficiency. The patient was then started on low-molecular-weight heparin, leading to improvement in the symptoms. Oral rivaroxaban was continued for the patient on discharge.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.54157