Nutritive profile, pharmaceutical potentials, and structural analysis of multifunctional bioactive fungal polysaccharides—A review

Asian nations have long used edible fungi as food and medicine. Polysaccharides are among the main building units of the cell walls of fungi. Fungal polysaccharides have been documented in the medicinal and industrial sectors as products with a vast array of various biological activities and applica...

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Published in:International journal of biological macromolecules 2024-05, Vol.266 (Pt 1), p.130893-130893, Article 130893
Main Authors: Elnahas, Marwa O., Elkhateeb, Waill A., Daba, Ghoson M.
Format: Article
Language:English
Subjects:
Animals
Antioxidants - chemistry
Antioxidants - pharmacology
Biological activities
Fungal Polysaccharides - chemistry
Fungal Polysaccharides - pharmacology
Fungi - drug effects
Fungus
Humans
Nutritive Value
Polysaccharides
Polysaccharides - chemistry
Polysaccharides - pharmacology
Structure activity relationship
Structure analysis
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Summary:Asian nations have long used edible fungi as food and medicine. Polysaccharides are among the main building units of the cell walls of fungi. Fungal polysaccharides have been documented in the medicinal and industrial sectors as products with a vast array of various biological activities and applications such as antitumor, antioxidant, anticancer, immunomodulation, and antiviral activities, etc. The goal of this review is to give insights into the various biological activities of mushroom polysaccharides and their potential as a medicine for human health. The extraction, purity, and structural analysis of fungal polysaccharides were also reviewed in this work. Also, future prospective, and challenges for fungal polysaccharides in pharmaceutical applications can be found in this review. Overall, this review serves as a valuable resource in exploring the therapeutic potential and applications of fungal polysaccharides. By building upon the existing knowledge base and addressing critical research gaps, researchers can find new opportunities for utilizing fungal polysaccharides as valuable therapeutic agents and functional ingredients in pharmaceuticals, nutraceuticals, and biotechnology. [Display omitted]
ISSN:0141-8130
1879-0003
DOI:10.1016/j.ijbiomac.2024.130893