Diagnosis and management of anemia in pediatric inflammatory bowel diseases: Clinical practice guidelines on behalf of the SIGENP IBD Working group

Anemia is one of the most frequent extra-intestinal manifestations of inflammatory bowel disease. Insidious onset, variability of symptoms and lack of standardized screening practices may increase the risk of underestimating its burden in children with IBD. Despite its relevance and peculiarity in e...

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Published in:Digestive and liver disease 2024-08, Vol.56 (8), p.1257-1269
Main Authors: Martinelli, Massimo, Fioretti, Maria Teresa, Aloi, Marina, Alvisi, Patrizia, Arrigo, Serena, Banzato, Claudia, Bramuzzo, Matteo, Campanozzi, Angelo, Civitelli, Fortunata, Knafelz, Daniela, Lionetti, Paolo, Marseglia, Antonio, Musto, Francesca, Norsa, Lorenzo, Palumbo, Giuseppe, Renzo, Sara, Romano, Claudio, Sansotta, Naire, Strisciuglio, Caterina, Miele, Erasmo
Format: Article
Language:English
Subjects:
Anemia - diagnosis
Anemia - etiology
Anemia - therapy
Anemia of chronic disease
Child
Childhood
Gastroenterology - standards
Humans
Inflammatory bowel disease
Inflammatory Bowel Diseases - complications
Inflammatory Bowel Diseases - diagnosis
Iron-deficiency anemia
Italy
Pediatrics
Societies, Medical
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Summary:Anemia is one of the most frequent extra-intestinal manifestations of inflammatory bowel disease. Insidious onset, variability of symptoms and lack of standardized screening practices may increase the risk of underestimating its burden in children with IBD. Despite its relevance and peculiarity in everyday clinical practice, this topic is only dealt with in a few documents specifically for the pediatric field. The aim of the current guidelines is therefore to provide pediatric gastroenterologists with a practical update to support the clinical and therapeutic management of children with IBD and anemia. A panel of 19 pediatric gastroenterologists and 1 pediatric hematologist with experience in the field of pediatric IBD was agreed by IBD Working group of the Italian Society of Gastroenterology, Hepatology and Nutrition (SIGENP) to produce the present article outlining practical clinical approaches to the pediatric patient with IBD and anemia. The levels of evidence and recommendations have been defined for each part of the statement according to the GRADE system.
ISSN:1590-8658
1878-3562
1878-3562
DOI:10.1016/j.dld.2024.02.016