The Use of Proton and Carbon Ion Radiation Therapy for Sarcomas

The unique physical and biological characteristics of proton and carbon ions allow for improved sparing of normal tissues, decreased integral dose to the body, and increased biological effect through high linear energy transfer. These properties are particularly useful for sarcomas given their histo...

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Bibliographic Details
Published in:Seminars in radiation oncology 2024-04, Vol.34 (2), p.207-217
Main Authors: Ioakeim-Ioannidou, Myrsini, Rose, Melanie, Chen, Yen-Lin, MacDonald, Shannon M.
Format: Article
Language:English
Subjects:
Heavy Ion Radiotherapy
Humans
Proton Therapy
Protons
Sarcoma - radiotherapy
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Summary:The unique physical and biological characteristics of proton and carbon ions allow for improved sparing of normal tissues, decreased integral dose to the body, and increased biological effect through high linear energy transfer. These properties are particularly useful for sarcomas given their histology, wide array of locations, and age of diagnosis. This review summarizes the literature and describes the clinical situations in which these heavy particles have advantages for treating sarcomas.
ISSN:1053-4296
1532-9461
DOI:10.1016/j.semradonc.2024.02.003