The relationship between C-reactive protein/albumin ratio and mortality in hypertensive patients: A national cohort study

The impact of inflammation on the prognosis of hypertension has received some attention. The current study examined the association between C-reactive protein to albumin ratio (CAR), a novel indicator of inflammatory response, and mortality in individuals with hypertension. A total of 9561 eligible...

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Bibliographic Details
Published in:Nutrition, metabolism, and cardiovascular diseases metabolism, and cardiovascular diseases, 2024-07, Vol.34 (7), p.1601-1609
Main Authors: Zhang, Rongting, Wang, Yani, Liao, Lihua, Liao, Ying, Fang, Yong, Shen, Yunli
Format: Article
Language:English
Subjects:
C-reactive protein/albumin ratio
Hypertension
Inflammation
Mortality
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Summary:The impact of inflammation on the prognosis of hypertension has received some attention. The current study examined the association between C-reactive protein to albumin ratio (CAR), a novel indicator of inflammatory response, and mortality in individuals with hypertension. A total of 9561 eligible individuals diagnosed with hypertension were included in the final analysis. CAR was calculated as ratio of C-reactive protein to serum albumin concentration. Patients were categorized into tertiles based on their baseline CAR levels. The Kaplan-Meier survival method was employed to compare the survival times of patients throughout the follow-up period. Multivariable analysis was conducted using the Cox proportional regression model. In the entire study population, 3262 (27%) experienced all-cause mortality. Patients in tertile 3 exhibited a higher risk of mortality (23% vs. 28% vs. 31%, P 
ISSN:0939-4753
1590-3729
1590-3729
DOI:10.1016/j.numecd.2024.02.011