Engineering better artificial chromosomes

Constructing human artificial chromosomes in yeast avoids unintended multimerization.

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 2024-03, Vol.383 (6689), p.1292-1293
Main Author: Dawe, R Kelly
Format: Article
Language:English
Subjects:
Alternative technology
Artificial chromosomes
Cell lines
Centromeres
Chromosomes
Chromosomes, Artificial - genetics
Chromosomes, Artificial, Human - genetics
Genomes
Human artificial chromosomes
Humans
Saccharomyces cerevisiae - genetics
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Description
Summary:Constructing human artificial chromosomes in yeast avoids unintended multimerization.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.ado4328