The 1st EoETALY Consensus on the Diagnosis and Management of Eosinophilic Esophagitis–Current Treatment and Monitoring

• Published in: Digestive and liver disease 2024-07, Vol.56 (7), p.1173-1184
• Main Authors: de Bortoli, Nicola, Visaggi, Pierfrancesco, Penagini, Roberto, Annibale, Bruno, Baiano Svizzero, Federica, Barbara, Giovanni, Bartolo, Ottavia, Battaglia, Edda, Di Sabatino, Antonio, De Angelis, Paola, Docimo, Ludovico, Frazzoni, Marzio, Furnari, Manuele, Iori, Andrea, Iovino, Paola, Lenti, Marco Vincenzo, Marabotto, Elisa, Marasco, Giovanni, Mauro, Aurelio, Oliva, Salvatore, Pellegatta, Gaia, Pesce, Marcella, Privitera, Antonino Carlo, Puxeddu, Ilaria, Racca, Francesca, Ribolsi, Mentore, Ridolo, Erminia, Russo, Salvatore, Sarnelli, Giovanni, Tolone, Salvatore, Zentilin, Patrizia, Zingone, Fabiana, Barberio, Brigida, Ghisa, Matteo, Savarino, Edoardo Vincenzo
• Format: Article
• Language: English
• Subjects: Consensus; Delphi Technique; EoE; EoETALY; Eosinophilic esophagitis; Eosinophilic Esophagitis - diagnosis; Eosinophilic Esophagitis - therapy; Guidelines; Humans; Italy; Proton Pump Inhibitors - therapeutic use
• ISSN: 1590-8658; 1878-3562; 1878-3562
• DOI: 10.1016/j.dld.2024.02.020

The present document constitutes Part 2 of the EoETALY Consensus Statements guideline on the diagnosis and management of eosinophilic esophagitis (EoE) developed by experts in the field of EoE across Italy (i.e., EoETALY Consensus Group). Part 1 was published as a different document, and included three chapters discussing 1) definition, epidemiology, and pathogenesis; 2) clinical presentation and natural history and 3) diagnosis of EoE. The present work provides guidelines on the management of EoE in two final chapters: 4) treatment and 5) monitoring and follow-up, and also includes considerations on knowledge gaps and a proposed research agenda for the coming years. The guideline was developed through a Delphi process, with grading of the strength and quality of the evidence of the recommendations performed according to accepted GRADE criteria.This document has received the endorsement of three Italian national societies including the Italian Society of Gastroenterology (SIGE), the Italian Society of Neurogastroenterology and Motility (SINGEM), and the Italian Society of Allergology, Asthma, and Clinical Immunology (SIAAIC). The guidelines also involved the contribution of members of ESEO Italia, the Italian Association of Families Against EoE.