Antibacterial Activity of Silver-Hydroxyapatite/Titania Nanoparticles on Oral Bacteria
Since bacterial accumulation surrounding biomaterials has pathogens known to cause the biomaterials centered infection, it may be important to develop some kind of biomaterial with antibacterial activity as well as biocompatibility. This study focused on evaluating the antibacterial activity of silv...
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Published in: | Key engineering materials 2007-01, Vol.330-332, p.299-302 |
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Main Authors: | , , , , , |
Format: | Article |
Language: | English |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Since bacterial accumulation surrounding biomaterials has pathogens known to cause the
biomaterials centered infection, it may be important to develop some kind of biomaterial with
antibacterial activity as well as biocompatibility. This study focused on evaluating the antibacterial
activity of silver-hydroxyapatite/ Titania nanoparticles (Ag-nHA/nTiO2) against oral bacteria with
agar dilution method. Bacteria were seeded on agar plate containing antibacterial material with
different concentrations after incubation of 48 hours. The antibacterial activity was demonstrated by
MICs. The MICs of Ag-nHA/nTiO2 ranged between 1000μg/ ml and 7500μg /ml under anaerobic
conditions. And it also exhibited remarkable antibacterial activity to all the aerobe bacteria
(MIC≤500μg/ml). On the other hand, the antibacterial activities of Ag-nHA/nTiO2 differentiate to
some extent with the bacterial strains. This Ag-nHA/nTiO2 exhibited remarkable antibacterial
activity to anaerobic and aerobe bacteria. This antibacterial effect may reduce the potential for
bacterial colonisation of oral biomaterials with Ag-nHA/nTiO2. |
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ISSN: | 1013-9826 1662-9795 1662-9795 |
DOI: | 10.4028/www.scientific.net/KEM.330-332.299 |