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Preparation of Macroporous Hydroxyapatite/Chitosan-Alginate Composite Scaffolds for Bone Implants
Porous HAp/chitosan-alginate composite scaffolds were successfully synthesized by insitu co-precipitation method. During the preparation of HAp/chitosan-alginate composite scaffolds, the interaction between chitosan-alginate molecules would be reduced with increasing HAp content, with the resulting...
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Published in: | Key engineering materials 2007-07, Vol.342-343, p.217-220 |
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Main Authors: | , , , , |
Format: | Article |
Language: | English |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Porous HAp/chitosan-alginate composite scaffolds were successfully synthesized by insitu
co-precipitation method. During the preparation of HAp/chitosan-alginate composite scaffolds,
the interaction between chitosan-alginate molecules would be reduced with increasing HAp content,
with the resulting that the chitosan-alginate molecules were homogeneously dispersed in the
composite scaffolds. The chitosan-alginate content was found to be almost consistent as initially
added during the preparation. These results imply that chitosan-alginate was almost perfectly
incorporated into the composites. It was found that the pore structure of the composite scaffolds
with low HAp content was similar to chitosan-alginate scaffolds, and the morphology of uniform
microstructure was unaffected by the presence of HAp. However, the pore diameter decreased with
increasing the HAp content up to HAp content of 30 wt%, eventually the pore structure was
collapsed and the composites scaffolds appeared to be agglomerated at higher HAp content. |
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ISSN: | 1013-9826 1662-9795 1662-9795 |
DOI: | 10.4028/www.scientific.net/KEM.342-343.217 |