The late effects of haematopoietic stem cell transplants in paediatric patients: a 25 year review

A rare, large single centre study covering all long-term health outcomes of paediatric allogeneic HSCT survivors, to provide comprehensive local data, and identify gaps and future directions for improved care. To document endocrine sequelae and other late effects of all HSCT recipients. Retrospectiv...

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Bibliographic Details
Published in:The journal of clinical endocrinology and metabolism 2024-03
Main Authors: Lee, Samantha Lai-Ka, Nguyen, Quynh-Nhu, Ho, Cindy, James, Simon, Kaur, Amreeta, Lim, Angelina, Tiedemann, Karin, Zacharin, Margaret
Format: Article
Language:English
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Summary:A rare, large single centre study covering all long-term health outcomes of paediatric allogeneic HSCT survivors, to provide comprehensive local data, and identify gaps and future directions for improved care. To document endocrine sequelae and other late effects of all HSCT recipients. Retrospective review. Royal Children's Hospital Melbourne. 384 children and adolescents received HSCT. 228 formed the study cohort; 212 were alive at commencement of data accrual. None. Incidence of endocrinopathies; fertility, growth, bone and metabolic status; subsequent malignant neoplasms (SMNs). Gonadotoxicity was more common in females (p
ISSN:1945-7197
DOI:10.1210/clinem/dgae196