Neurocognition and brain functional connectivity in a non-clinical population-based sample with psychotic experiences

We characterized the neurocognitive profile of communed-based individuals and unaffected siblings of patients with psychosis from Brazil reporting psychotic experiences (PEs). We also analyzed associations between PEs and the intra and inter-functional connectivity (FC) in the Default Mode Network (...

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Bibliographic Details
Published in:Schizophrenia research 2024-05, Vol.267, p.156-164
Main Authors: Ragazzi, Taciana Cristina Carvalho, Shuhama, Rosana, da Silva, Pedro Henrique Rodrigues, Corsi-Zuelli, Fabiana, Loureiro, Camila Marcelino, da Roza, Daiane Leite, Leoni, Renata Ferranti, Menezes, Paulo Rossi, Del-Ben, Cristina Marta
Format: Article
Language:English
Subjects:
Adult
Brain - diagnostic imaging
Brain - physiopathology
Brazil
Cognitive Dysfunction - diagnostic imaging
Cognitive Dysfunction - etiology
Cognitive Dysfunction - physiopathology
Connectome
Default Mode Network - diagnostic imaging
Default Mode Network - physiopathology
Female
Fronto-parietal network
Functional connectivity
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Nerve Net - diagnostic imaging
Nerve Net - physiopathology
Neurocognitive
Processing speed
Psychotic Disorders - diagnostic imaging
Psychotic Disorders - physiopathology
Psychotic experiences
Siblings
Young Adult
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Summary:We characterized the neurocognitive profile of communed-based individuals and unaffected siblings of patients with psychosis from Brazil reporting psychotic experiences (PEs). We also analyzed associations between PEs and the intra and inter-functional connectivity (FC) in the Default Mode Network (DMN), the Fronto-Parietal Network (FPN) and the Salience Network (SN) measured by functional magnetic resonance imaging. The combined sample of communed-based individuals and unaffected siblings of patients with psychosis comprised 417 (neurocognition) and 85 (FC) volunteers who were divided as having low (
ISSN:0920-9964
1573-2509
1573-2509
DOI:10.1016/j.schres.2024.03.026