How Does Ultrasound Global OMERACT–EULAR Synovitis Score (GLOESS) for Rheumatoid Arthritis (RA) Activity Assessment Perform in Real‐Life?

• Published in: Journal of ultrasound in medicine 2024-07, Vol.43 (7), p.1313-1318
• Main Authors: Andrade, Nicole Pamplona Bueno, Brenol, Claiton Viegas, Silva Chakr, Rafael Mendonça
• Format: Article
• Language: English
• Subjects: Adult; Aged; Arthritis, Rheumatoid - diagnostic imaging; Cross-Sectional Studies; Female; GLOESS; Humans; Male; Metacarpophalangeal Joint - diagnostic imaging; Middle Aged; Reproducibility of Results; rheumatoid arthritis; Sensitivity and Specificity; Severity of Illness Index; synovitis; Synovitis - diagnostic imaging; Ultrasonography - methods; ultrasound
• ISSN: 0278-4297; 1550-9613
• DOI: 10.1002/jum.16455

Objective This study aimed to assess the effectiveness of the Global OMERACT–EULAR Synovitis Score (GLOESS) of bilateral second to fifth metacarpophalangeal joints (MCP 2–5) in evaluating rheumatoid arthritis (RA) activity in a real‐life setting. Methods This cross‐sectional study included consecutive RA patients without hyperalgesia. Clinical data were extracted from electronic medical records. Evaluations were conducted on bilateral MCP 2–5 by two independent experts in musculoskeletal ultrasound (MSUS). Correlation between clinical and ultrasonographic parameters was analyzed, aiming to define a cutoff value for detecting disease activity. Results Sixty‐nine patients were included. The mean DAS28‐ESR was 4.3 (±1.4), and the median GLOESS was 7 (13). The correlation between GLOESS and DAS28 was moderate (r = .62; P