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Paradoxical Adipose Hyperplasia Following Cryolipolysis

Cryolipolysis (CL) is a noninvasive technique in which applicators cool tissue to temperatures that selectively destroy adipocytes. Since its introduction to the market, it has rapidly become one of the leading nonsurgical modalities to reduce fat in the aesthetic industry. Paradoxical adipose hyper...

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Bibliographic Details
Published in:Aesthetic surgery journal 2024-09, Vol.44 (10), p.1063-1071
Main Authors: Stein, Michael J, Smith, Darren, Chia, Christopher, Matarasso, Alan
Format: Article
Language:English
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Summary:Cryolipolysis (CL) is a noninvasive technique in which applicators cool tissue to temperatures that selectively destroy adipocytes. Since its introduction to the market, it has rapidly become one of the leading nonsurgical modalities to reduce fat in the aesthetic industry. Paradoxical adipose hyperplasia (PAH) is a rare adverse reaction to CL, in which there is initial reduction in fat volume, followed by abnormal fat growth exceeding the original volume in the treated area. The incidence of PAH is thought to be underreported, and its pathophysiology and management remains unclear. The objective of this study was to present a series of PAH cases and review efficacy of management modalities.
ISSN:1090-820X
1527-330X
1527-330X
DOI:10.1093/asj/sjae077