Clinical Analysis of Risk Factors and Perinatal Outcomes in Recurrent Pre-Eclampsia with Severe Features

To analyze the differences in risk factors and pregnancy outcomes between recurrent and initial pre-eclampsia(PE) with severe features. Data from recurrent ( n  = 128) and initial ( n  = 904) PE with severe features who terminated their pregnancy or gave birth at 20 weeks of gestation or later at th...

Full description

Saved in:
Bibliographic Details
Published in:Reproductive sciences (Thousand Oaks, Calif.) Calif.), 2024-09, Vol.31 (9), p.2763-2770
Main Authors: Wu, Chengqian, Ling, Zhonghui, Wang, Yixiao, Lv, Yan, Miao, Zhijing, Liu, Lan, Ji, Xiaohong
Format: Article
Language:English
Subjects:
Adult
Cesarean Section
China - epidemiology
Embryology
Female
Humans
Infant, Newborn
Medicine
Medicine & Public Health
Obstetrics/Perinatology/Midwifery
Pre-Eclampsia - epidemiology
Pregnancy
Pregnancy Outcome - epidemiology
Pregnancy: Original Article
Recurrence
Reproductive Medicine
Retrospective Studies
Risk Factors
Severity of Illness Index
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To analyze the differences in risk factors and pregnancy outcomes between recurrent and initial pre-eclampsia(PE) with severe features. Data from recurrent ( n  = 128) and initial ( n  = 904) PE with severe features who terminated their pregnancy or gave birth at 20 weeks of gestation or later at the tertiary teaching hospital (Women’s Hospital of Nanjing Medical University, Nanjing Women and Children’s Healthcare Hospital) from January 2016 to December 2022 were collected. Risk factors for recurrent PE with severe features and differences in pregnancy outcomes between the two groups were assessed using the chi-square test, student t-test, or nonparametric test. Independent risk factors for recurrent PE with severe features were further analyzed by logistic regression. (1) Logistic regression analysis identified 3 independent risk factors for recurrent PE with severe features: history of cesarean section, rural residence and chronic hypertension. In addition, assisted reproductive technology (ART) is an independent risk factor for initial PE with severe features; (2) The incidence of oligohydramnios, chorioamnionitis, preterm birth, stillbirth, fetal growth restriction (FGR) and abnormal umbilical blood flow was higher in the recurrent PE with severe features group than in the initial PE with severe features group( P  
ISSN:1933-7191
1933-7205
1933-7205
DOI:10.1007/s43032-024-01529-4