Genetic architecture of preeclampsia

•Recent studies have implicated genes involved in placental development and cardiovascular conditions in predisposition to preeclampsia.•Genes associated with preeclampsia features such as proteinuria and hypertension are found to increase the susceptibility to preeclampsia.•Circadian genes altering...

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Bibliographic Details
Published in:Clinica chimica acta 2024-05, Vol.558, p.119656, Article 119656
Main Authors: Manoharan, Aarthi, Ballambattu, Vishnu Bhat, Palani, Ramya
Format: Article
Language:English
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Summary:•Recent studies have implicated genes involved in placental development and cardiovascular conditions in predisposition to preeclampsia.•Genes associated with preeclampsia features such as proteinuria and hypertension are found to increase the susceptibility to preeclampsia.•Circadian genes altering the sleep patterns and affecting trophoblast invasion may lead to preeclampsia.
ISSN:0009-8981
1873-3492
1873-3492
DOI:10.1016/j.cca.2024.119656