Photo-induced phosphorylation/cyclization of N -homoallyl and N -allyl aldehyde hydrazones to access phosphorylated tetrahydropyridazines and dihydropyrazoles

A photocatalytic radical carbophosphorylation/cyclization of -homoallyl aldehyde hydrazones with phosphine oxides was developed under metal-free conditions, achieving phosphorylated tetrahydropyridazines in yields up to 95%. Phosphorylated dihydropyrazoles were also constructed, by reacting -allyl a...

Full description

Saved in:
Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2024-04, Vol.60 (35), p.4687-4690
Main Authors: Liu, Lingli, Wu, Yechun, Xiang, Chengli, Yu, Jin-Tao, Pan, Changduo
Format: Article
Language:English
Subjects:
Aldehydes
Hydrazones
Phosphine oxide
Phosphorylation
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A photocatalytic radical carbophosphorylation/cyclization of -homoallyl aldehyde hydrazones with phosphine oxides was developed under metal-free conditions, achieving phosphorylated tetrahydropyridazines in yields up to 95%. Phosphorylated dihydropyrazoles were also constructed, by reacting -allyl aldehyde hydrazones with phosphine oxides under the same conditions.
ISSN:1359-7345
1364-548X
DOI:10.1039/d4cc00608a