2020 ASCO, 2023 NCCN, 2023 MASCC/ESMO, and 2019 CCO: a comparison of antiemetic guidelines for the treatment of chemotherapy-induced nausea and vomiting in cancer patients

Chemotherapy-induced nausea and vomiting (CINV) is a common toxicity that may impair the quality of life of patients with various malignancies ranging from early to end stages. In light of frequent changes to the guidelines for optimal management of CINV, we undertook this narrative review to compar...

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Published in:Supportive care in cancer 2024-05, Vol.32 (5), p.280-280, Article 280
Main Authors: Kennedy, Samantha K. F., Goodall, Shannon, Lee, Shing Fung, DeAngelis, Carlo, Jocko, Allison, Charbonneau, Flay, Wang, Katie, Pasetka, Mark, Ko, Yoo-Joung, Wong, Henry C. Y., Chan, Adrian Wai, Rajeswaran, Thenugaa, Gojsevic, Milena, Chow, Edward, Gralla, Richard J., Ng, Terry L., Jerzak, Katarzyna J.
Format: Article
Language:English
Subjects:
Antiemetics
Antiemetics - pharmacology
Antineoplastic Agents - adverse effects
Chemotherapy
Clinical practice guidelines
Humans
Medicine
Medicine & Public Health
Nausea
Nausea - chemically induced
Nausea - drug therapy
Nausea - prevention & control
Neoplasms - drug therapy
Nursing
Nursing Research
Oncology
Pain Medicine
Quality of Life
Rehabilitation Medicine
Review
Side effects
Vomiting
Vomiting - chemically induced
Vomiting - drug therapy
Vomiting - prevention & control
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Summary:Chemotherapy-induced nausea and vomiting (CINV) is a common toxicity that may impair the quality of life of patients with various malignancies ranging from early to end stages. In light of frequent changes to the guidelines for optimal management of CINV, we undertook this narrative review to compare the most recent guidelines published by ASCO (2020), NCCN (2023), MASCC/ESMO (2023), and CCO (2019). The processes undertaken by each organization to evaluate existing literature were also described. Although ASCO, NCCN, MASCC/ESMO, and CCO guidelines for the treatment and prevention of CINV share many fundamental similarities, the literature surrounding low and minimal emetic risk regimens is lacking. Current data regarding adherence to these guidelines is poor and warrants further investigation to improve care.
ISSN:0941-4355
1433-7339
DOI:10.1007/s00520-024-08462-x