Comparison of muscle and fat parameters measured by ultrasonography and dual‐energy x‐ray absorptiometry between older palliative care patients with and without type 2 diabetes mellitus

• Published in: Journal of clinical ultrasound 2024-06, Vol.52 (5), p.608-618
• Main Authors: Catikkas, Nezahat Muge, Safer, Vildan Binay, Bas, Suleyman, Gunay, Deniz Sevindik, Durak, Ayfer, Utku, Irem Kirac, Safer, Umut
• Format: Article
• Language: English
• Subjects: Absorptiometry, Photon - methods; Adipose Tissue - diagnostic imaging; Aged; Aged, 80 and over; Blood pressure; Body Composition; Body mass index; Body size; Comorbidity; Composition; Confidence intervals; Cross-Sectional Studies; Demographics; Diabetes; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - physiopathology; Dual energy X-ray absorptiometry; Female; Humans; Male; Microvasculature; Muscle, Skeletal - diagnostic imaging; Muscles; Nutritional status; older; Palliation; Palliative care; Palliative Care - methods; Parameters; prospective; Prospective Studies; rectus femoris muscle thickness; Regression analysis; Statistical analysis; Thickness; Ultrasonic imaging; ultrasonography; Ultrasonography - methods
• ISSN: 0091-2751; 1097-0096
• DOI: 10.1002/jcu.23688

Background and Aims There are limited data on the comparison of body compositions between diabetic and non‐diabetic patients. We aimed to compare the muscle mass and fat parameters measured by ultrasonography (USG) and dual‐energy x‐ray absorptiometry (DXA) between older palliative care patients with and without type 2 diabetes mellitus (DM). Methods We conducted a prospective, cross‐sectional study. We recorded the demographics, comorbidities, blood pressures, microvascular complications, pressure injuries, ambulation and nutritional status, and laboratory parameters. We measured the handgrip strength with a hand dynamometer and anthropometric parameters. We analyzed the subcutaneous fat thickness, muscle thickness (MT), and cross‐sectional area (CSA) of the rectus femoris (RF) and biceps brachii muscles by USG and the total and regional muscle mass and fat parameters by DXA. We performed a regression analysis to examine the independently associated factors of DM. Results We included 55 patients (mean age: 79.0 ± 8.0 years, 56.4%: female). 43.6% had type 2 DM. The patients with DM had significantly higher glucose and HbA1c levels and lower RFMT and RFCSA values than the patients without DM (p