Prognostic Implications of N-Terminal Pro-B-Type Natriuretic Peptide in Patients With Non-ST-Elevation Myocardial Infarction

Background: Limited data exist regarding the prognostic implications of N-terminal pro-B-type natriuretic peptide (NT-proBNP) in patients with non-ST-elevation myocardial infarction (NSTEMI) who undergo percutaneous coronary intervention (PCI).Methods and Results: Of 13,104 patients in the nationwid...

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Published in:Circulation Journal 2024/07/25, Vol.88(8), pp.1237-1245
Main Authors: Kim, Chang Hoon, Lee, Seung Hun, Kim, Hyun Kuk, Kim, Min Chul, Kim, Ju Han, Hong, Young Joon, Ahn, Young Keun, Jeong, Myung Ho, Hur, Seung Ho, Kim, Doo Il, Chang, Kiyuk, Park, Hun Sik, Bae, Jang-Whan, Jeong, Jin-Ok, Park, Yong Hwan, Yun, Kyeong Ho, Yoon, Chang-Hwan, Kim, Yisik, Hwang, Jin-Yong, Kim, Hyo-Soo, Choi, Ki Hong, Park, Taek Kyu, Yang, Jeong Hoon, Song, Young Bin, Hahn, Joo-Yong, Choi, Seung-Hyuk, Gwon, Hyeon-Cheol, Lee, Joo Myung, Investigators, The KAMIR-NIH
Format: Article
Language:English
Subjects:
Acute myocardial infarction
Aged
Biomarkers
Biomarkers - blood
Coronary intervention
Female
Heart Failure - blood
Heart Failure - mortality
Humans
Male
Middle Aged
Natriuretic Peptide, Brain - blood
Non-ST Elevated Myocardial Infarction - blood
Non-ST Elevated Myocardial Infarction - diagnosis
Non-ST Elevated Myocardial Infarction - mortality
Non-ST Elevated Myocardial Infarction - therapy
Non-ST-elevation myocardial infarction
Peptide Fragments - blood
Percutaneous Coronary Intervention
Prognosis
Registries
Republic of Korea - epidemiology
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Summary:Background: Limited data exist regarding the prognostic implications of N-terminal pro-B-type natriuretic peptide (NT-proBNP) in patients with non-ST-elevation myocardial infarction (NSTEMI) who undergo percutaneous coronary intervention (PCI).Methods and Results: Of 13,104 patients in the nationwide Korea Acute Myocardial Infarction Registry-National Institutes of Health, 3,083 patients with NSTEMI who underwent PCI were included in the present study. The primary endpoint was major adverse cardiovascular events (MACE) at 3 years, a composite of all-cause death, recurrent myocardial infarction, unplanned repeat revascularization, and admission for heart failure. NT-proBNP was measured at the time of initial presentation for the management of NSTEMI, and patients were divided into a low (
ISSN:1346-9843
1347-4820
1347-4820
DOI:10.1253/circj.CJ-24-0129