The Repeatability of Pharyngeal Opening Pressure Under Drug‐Induced Sleep Endoscopy

• Published in: Otolaryngology-head and neck surgery 2024-07, Vol.171 (1), p.295-302
• Main Authors: Chan, Tyler G., Plageman, Jack, Yu, Jason L.
• Format: Article
• Language: English
• Subjects: drug‐induced sleep endoscopy; obstructive sleep apnea; pharyngeal opening pressure; repeatable measures; upper airway collapsibility
• ISSN: 0194-5998; 1097-6817; 1097-6817
• DOI: 10.1002/ohn.730

Objective Pharyngeal opening pressure (PhOP) is a measure of upper airway collapsibility that can be obtained during drug‐induced sleep endoscopy (DISE) using a continuous positive airway pressure (CPAP) titration. However, the stability of PhOP over the course of sedation during DISE remains unclear. This study aims to compare repeat measures of PhOP over the course of DISE. Study Design Single arm prospective study. Setting Single tertiary care institution. Methods Patients had 2 CPAP titrations while undergoing DISE. Collected data included patient demographics, PhOP, patient sedation index (PSI), and duration of and between CPAP titrations. t Tests, test‐retest coefficient analysis, and repeated measures correlation were performed. Results Twenty‐five patients completed the study between 2022 and 2023 with 22 patients having sedation depth (PSI) recording. Most were male (76%), obese (average body mass index: 30.24 kg/m2), with severe obstructive sleep apnea (average apnea‐hypopnea index: 39.8 events/hr). Test‐retest analysis showed good‐excellent correlation between PhOP values (intraclass correlation coefficient = 0.892, P