Comparing the morphology of optic nerve head and lamina cribrosa in full-term and preterm school-aged children

Objectives To evaluate the morphology of lamina cribrosa (LC) in preterm school-aged children. Methods A study of 120 eyes from 120 patients, including 42 full-term children (control group), 41 preterm children without retinopathy of prematurity (ROP), 16 children with ROP treated with intravitreal...

Full description

Saved in:
Bibliographic Details
Published in:Eye (London) 2024-07, Vol.38 (10), p.1964-1970
Main Authors: Lee, Yung-Sung, Kang, Eugene Yu-Chuan, Chen, Henry Shen-Lih, Yeh, Po‑Han, Wu, Wei-Chi
Format: Article
Language:English
Subjects:
692/698/1688/512/2613
706/648/160
Age composition
Bevacizumab
Children
Laboratory Medicine
Medicine
Medicine & Public Health
Morphology
Ophthalmology
Optic nerve
Pharmaceutical Sciences/Technology
Retinopathy
Surgery
Surgical Oncology
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objectives To evaluate the morphology of lamina cribrosa (LC) in preterm school-aged children. Methods A study of 120 eyes from 120 patients, including 42 full-term children (control group), 41 preterm children without retinopathy of prematurity (ROP), 16 children with ROP treated with intravitreal bevacizumab (IVB), and 21 children with ROP treated with laser. Five parameters of LC were measured by optical coherence tomography, including Bruch’s membrane opening (BMO) diameter, minimum rim width (MRW), LC depth, prelaminar tissue (PLT) thickness, and LC curvature index (LCCI). Results The PLT thickness increased with age in full-term and preterm children (β = 30.1, P  = 0.003 and β = 19.6, P  
ISSN:0950-222X
1476-5454
1476-5454
DOI:10.1038/s41433-024-03053-w