Non coding RNA therapeutics in the treatment of heart failure

ncRNA therapeutics can target either ncRNAs or conventional mRNA, offering both superior pharmacokinetics and selectivity to conventional therapies and addressing new, previously unexplored pathways. Although no ncRNA has yet been approved for the treatment of heart failure, in this review we presen...

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Bibliographic Details
Published in:European heart journal. Cardiovascular pharmacotherapy 2024-07, Vol.10 (4), p.353-360
Main Authors: Paterek, Aleksandra, Załęska-Kocięcka, Marta, Surzykiewicz, Mateusz, Wojdyńska, Zuzanna, Leszek, Przemysław, Mączewski, Michał
Format: Article
Language:English
Subjects:
Drug therapy
Heart failure
Homeopathy
Materia medica and therapeutics
Messenger RNA
MicroRNA
Natriuretic peptides
Patient compliance
Therapeutics
Citations: Items that this one cites
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Summary:ncRNA therapeutics can target either ncRNAs or conventional mRNA, offering both superior pharmacokinetics and selectivity to conventional therapies and addressing new, previously unexplored pathways. Although no ncRNA has yet been approved for the treatment of heart failure, in this review we present 5 most promising pathways and agents that are either in human clinical trials or offer great promise in the near future.
ISSN:2055-6837
2055-6845
2055-6845
DOI:10.1093/ehjcvp/pvae027