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A high-performance chiral 19F-labeled probe with an increased structural twisting

We developed a new strategy to enhance the chiral discrimination capability of 19F-labeled probes by tuning the torsion angle of the probe's backbone, allowing for the resolution of challenging analytes. Its versatility is demonstrated through the superior performance and the wide analyte scope...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2024-05, Vol.60 (38), p.5082-5085
Main Authors: Wang, Chenyang, Gu, Guangxing, Zhang, Wei, Wu, Jian, Zhao, Yanchuan
Format: Article
Language:English
Online Access:Get full text
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Summary:We developed a new strategy to enhance the chiral discrimination capability of 19F-labeled probes by tuning the torsion angle of the probe's backbone, allowing for the resolution of challenging analytes. Its versatility is demonstrated through the superior performance and the wide analyte scope.
ISSN:1359-7345
1364-548X
DOI:10.1039/d4cc01313a