Severe acute respiratory syndrome coronavirus 2 infection rate among pediatric patients with respiratory symptoms

• Published in: Pediatrics international 2024-01, Vol.66 (1), p.e15740-e15740
• Main Authors: Samerton, Penpitcha, Apiwattanakul, Nopporn, Assawawiroonhakarn, Surapat, Sahakijpicharn, Thiantip, Thongchai, Rakruthai, Techasaensiri, Chonnamet, Boonsathorn, Sophida, Chaisavaneeyakorn, Sujittra
• Format: Article
• Language: English
• Subjects: Chest Pain; Child; Child, Preschool; Cough - epidemiology; Cough - etiology; COVID-19 - epidemiology; Cross-Sectional Studies; Dyspnea; Female; Humans; Male; Obesity; Post-Acute COVID-19 Syndrome; Prospective Studies; SARS-CoV-2
• ISSN: 1328-8067; 1442-200X
• DOI: 10.1111/ped.15740

The incidence of coronavirus disease 2019 (COVID-19) in children has been increasing worldwide since the onset of the pandemic. This study examined the risk factors and characteristics of COVID-19 among pediatric patients compared to other respiratory viral infections. This was a prospective cross-sectional study. Patients aged 0-18 years presenting with respiratory symptoms from October 2020 to December 2021 were included. Demographic and clinical data were reviewed. In total, 738 pediatric patients were enrolled. Of these, 48.5% had COVID-19, and 41.3% were infected with another respiratory virus. The COVID-19 incidence increased from 0.5% during the original strain outbreak (October 2020 to March 2021) to 56.5% and 73.4% during the alpha (April to June 2021) and delta (July to December 2021) periods, respectively. Children aged 6-18 years, being female, obesity, exposure to household members with COVID-19, and the delta period were risk factors for COVID-19. Being aged 1-5 years, obesity, shortness of breath, productive cough, and chest pain were associated with COVID-19 pneumonia. Children aged 5-18 years, underlying neurological disease, a history of COVID-19 pneumonia, and the delta period were associated with long COVID. Pediatric COVID-19 patients presenting with respiratory symptoms who are obese or have been exposed to household members with COVID-19 should be tested for COVID-19. COVID-19 patients who are obese, younger than five years old, or who present with shortness of breath, productive cough, or chest pain should be evaluated for pneumonia. COVID-19 patients with a history of COVID-19 pneumonia or underlying neurological disease should receive follow-up for long COVID.