Elevated skull fractures: an institutional experience and individual participant data meta-analysis

Elevated skull fracture (ESF) is a rare but potentially life-threatening type of skull fracture. The literature on this topic is relatively sparse. Herein, we conducted a meta-analysis of all the patients reported in the literature with ESFs with respect to their clinical management to better inform...

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Published in:Neurosurgical review 2024-04, Vol.47 (1), p.178-178, Article 178
Main Authors: Zoghi, Sina, Habibzadeh, Adrina, Ansari, Ali, Still, Megan E. H., Lu, Victor M., Tabesh, Zahra, Masoudi, Mohammad Sadegh, Taheri, Reza
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Language:English
Subjects:
Adolescent
Adult
Female
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Neurosurgery
Retrospective Studies
Skull Fractures - surgery
Young Adult
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creator Zoghi, Sina
Habibzadeh, Adrina
Ansari, Ali
Still, Megan E. H.
Lu, Victor M.
Tabesh, Zahra
Masoudi, Mohammad Sadegh
Taheri, Reza
description Elevated skull fracture (ESF) is a rare but potentially life-threatening type of skull fracture. The literature on this topic is relatively sparse. Herein, we conducted a meta-analysis of all the patients reported in the literature with ESFs with respect to their clinical management to better inform practice. On 20th of January 2023, we conducted a systematic search of literature to find all published cases of ESF. We also conducted a retrospective review of ESF cases from our institution. The data collection and analysis were conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. After screening, 28 studies met the inclusion criteria. A total of 104 individual patients were included in the meta-analysis, with a median age of 24 years and 85.7% of whom were males. 11 patients (11.2%) had an unfavorable outcome while 37 (35.2%) had one or more complications. We found that GCS on admission is an independent predictor of poor outcome in ESF (odds ratio (95% confidence interval) = 1.605 (1.110–2.315), p value = 0.012). Regarding complications, dural injury (odds ratio (95% confidence interval) = 66.667 (7.407-500.00), p value 
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subjects Adolescent
Adult
Female
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Neurosurgery
Retrospective Studies
Skull Fractures - surgery
Young Adult
title Elevated skull fractures: an institutional experience and individual participant data meta-analysis
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