Predictive value of neutrophil gelatinase-associated lipocalin (NGAL) values for cardiac arrest outcomes: A systematic review and meta-analysis

The study by Park et al. found that the long-term survival rates of patients after OHCA were significantly lower in the high-NGAL group than in the low-NGAL group at each time point [9]. [...]the study by Choi et al. also found that the serum NGAL level measured in patients after OHCA is an excellen...

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Bibliographic Details
Published in:The American journal of emergency medicine 2024-06, Vol.80, p.221-223
Main Authors: Kurek, Krzysztof, Lepetit, Anne, Pruc, Michal, Surma, Stanislaw, Banach, Maciej, Rafique, Zubaid, Peacock, William Frank, Szarpak, Lukasz
Format: Article
Language:English
Subjects:
Biomarkers - blood
Cardiac arrest
Gelatinase
Heart Arrest - blood
Humans
Leukocytes (neutrophilic)
Lipocalin
Lipocalin-2 - blood
Lipocalin-2 - urine
Medical prognosis
Meta-analysis
Mortality
Neutrophils
Predictive Value of Tests
Prognosis
Survival
Systematic review
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Summary:The study by Park et al. found that the long-term survival rates of patients after OHCA were significantly lower in the high-NGAL group than in the low-NGAL group at each time point [9]. [...]the study by Choi et al. also found that the serum NGAL level measured in patients after OHCA is an excellent early predictive marker for AKI [10]. [...]we assessed the predictive ability of NGAL levels in terms of survival, survival with good neurological status, and the occurrence of AKI after OHCA. [...]12 studies were included in this meta-analysis.
ISSN:0735-6757
1532-8171
1532-8171
DOI:10.1016/j.ajem.2024.04.005