Relationship between the Fibrinogen/Albumin Ratio and Microvascular Perfusion in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction: A Prospective Study

Correct TIMI frame count (CTFC), myocardial blush grade (MBG), and ST-segment resolution (STR) are parameters used to evaluate reperfusion at the microvascular level in patients that have undergone primary percutaneous coronary intervention (pPCI). Fibrinogen-to-albumin ratio (FAR) has been associat...

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Published in:Arquivos brasileiros de cardiologia 2023-10, Vol.120 (11), p.e20230002-e20230002
Main Authors: Kaplangoray, Mustafa, Toprak, Kenan, Cicek, Omer Faruk, Deveci, Edhem
Format: Article
Language:eng ; por
Subjects:
Aged
Biomarkers - blood
Coronary Angiography
Coronary Circulation - physiology
Female
Fibrinogen - analysis
Humans
Male
Microcirculation - physiology
Middle Aged
Percutaneous Coronary Intervention - methods
Prospective Studies
Reference Values
ROC Curve
Serum Albumin - analysis
ST Elevation Myocardial Infarction - blood
ST Elevation Myocardial Infarction - physiopathology
ST Elevation Myocardial Infarction - surgery
Statistics, Nonparametric
Treatment Outcome
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Summary:Correct TIMI frame count (CTFC), myocardial blush grade (MBG), and ST-segment resolution (STR) are parameters used to evaluate reperfusion at the microvascular level in patients that have undergone primary percutaneous coronary intervention (pPCI). Fibrinogen-to-albumin ratio (FAR) has been associated with thrombotic events in patients with ST-elevation myocardial infarction (STEMI) and chronic venous insufficiency. To investigate the relationship of FAR with CTFC, MBG, and STR. Methods: The study included 167 consecutive patients who underwent successful pPCI for STEMI and achieved TIMI-3 flow. The cases were divided into two groups, high (>0.0765) and low FAR (≤0.0765), according to the cut-off value of this parameter in the receiver operator characteristic analysis (ROC). STR, CTFC, and MBG were used to evaluate myocardial reperfusion. P values
ISSN:1678-4170
DOI:10.36660/abc.20230002