Vision‐related quality of life in patients with glaucoma before and after trabeculectomy

• Published in: Acta ophthalmologica (Oxford, England) England), 2024-11, Vol.102 (7), p.779-789
• Main Authors: Arenstorff, Mathilde M., Ahmadzadeh, Afrouz, Schmidt, Bo Simmendefeldt, Kessel, Line, Bach‐Holm, Daniella
• Format: Article
• Language: English
• Subjects: Acuity; Aged; Female; Follow-Up Studies; Glaucoma; Glaucoma - physiopathology; Glaucoma - psychology; Glaucoma - surgery; Humans; Intraocular Pressure - physiology; Male; Middle Aged; Postoperative Period; Prospective Studies; Quality of Life; Sickness Impact Profile; Structure-function relationships; Surveys and Questionnaires; trabeculectomy; Trabeculectomy - methods; VFQ‐25; Vision; vision‐related quality of life; Visual Acuity - physiology; Visual Fields - physiology; Visual perception
• ISSN: 1755-375X; 1755-3768; 1755-3768
• DOI: 10.1111/aos.16697

Purpose To determine vision‐related quality of life (VR‐QoL) and functional and structural parameters associated with VR‐QoL in patients with glaucoma before and 12 months after trabeculectomy. Methods Fifty‐eight patients undergoing trabeculectomy were included. Participants completed the 25‐item National Eye Institute Visual Function Questionnaire (VFQ‐25) prior to and 12 months after trabeculectomy. Functional (visual acuity and visual fields) and structural (ganglion cell layer volume) parameters were evaluated for their association with VR‐QoL using multiple linear regression of VFQ‐25 subscale scores. Intraocular pressure and the number of glaucoma medications were also included in the analyses. Results The VFQ‐25 composite score did not change after trabeculectomy (before: 74.9; 12 months: 74.0; p = 0.512). The subscale mental health had a significantly higher score 12 months after trabeculectomy (before: 65.6; 12 months: 71.4; p = 0.017). The VFQ‐25 scores for general health (before: 68.5; 12 months: 62.5; p = 0.009) and role difficulties (before: 78.9; 12 months: 53.7; p