Metal-Free ortho C–H Borylation of Thiobenzamides

A BBr3-mediated S-directed ortho C–H borylation of thiobenzamides was developed. A variety of ortho-borylated thiobenzamides were obtained in moderate to good yields with a wide functional group tolerance under simple and metal-free conditions. This transformation provided a convenient and practical...

Full description

Saved in:
Bibliographic Details
Published in:Organic letters 2024-05, Vol.26 (18), p.3709-3714
Main Authors: Lv, Jianxing, Liang, Yixuan, Ouyang, Yepeng, Zhang, Hua
Format: Article
Language:English
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A BBr3-mediated S-directed ortho C–H borylation of thiobenzamides was developed. A variety of ortho-borylated thiobenzamides were obtained in moderate to good yields with a wide functional group tolerance under simple and metal-free conditions. This transformation provided a convenient and practical route to important functionalized thiobenzamides.
ISSN:1523-7060
1523-7052
DOI:10.1021/acs.orglett.4c00691