Impact of anemia on outcomes and resource utilization in patients with myocardial infarction: A national database analysis

Although anemia is common in patients with myocardial infarction (MI), management remains controversial. We quantified the association of anemia with in-hospital outcomes and resource utilization in patients admitted with MI using a large national database. All hospitalizations with a primary diagno...

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Bibliographic Details
Published in:International journal of cardiology 2024-08, Vol.408, p.132111-132111, Article 132111
Main Authors: Jhand, Aravdeep S., Abusnina, Waiel, Tak, Hyo Jung, Ahmed, Arslan, Ismayl, Mahmoud, Altin, S. Elissa, Sherwood, Matthew W., Alexander, John H., Rao, Sunil V., Abbott, J. Dawn, Carson, Jeffrey L., Goldsweig, Andrew M.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Anemia
Anemia - economics
Anemia - epidemiology
Anemia - therapy
Cost
Databases, Factual
Female
Health Resources - economics
Health Resources - statistics & numerical data
Hospital Mortality - trends
Hospitalization - economics
Hospitalization - statistics & numerical data
Humans
Length of Stay - statistics & numerical data
Male
Middle Aged
Mortality
Myocardial infarction
Myocardial Infarction - complications
Myocardial Infarction - economics
Myocardial Infarction - epidemiology
Myocardial Infarction - therapy
National Inpatient Sample
Retrospective Studies
Transfusion
United States - epidemiology
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Summary:Although anemia is common in patients with myocardial infarction (MI), management remains controversial. We quantified the association of anemia with in-hospital outcomes and resource utilization in patients admitted with MI using a large national database. All hospitalizations with a primary diagnosis code for acute MI in the National Inpatient Sample (NIS) between 2014 and 2018 were identified. Among these hospitalizations, patients with anemia were identified using a secondary diagnosis code. Data on demographic and clinical variables were collected. Outcomes of interest included in-hospital adverse events, length of stay (LOS), and total cost. Multivariable logistic regression and generalized linear models were used to evaluate the relationship between anemia and outcomes. Among 1,113,181 MI hospitalizations, 254,816 (22.8%) included concomitant anemia. Anemic patients were older and more likely to be women. After adjustment for demographics and comorbidities, anemia was associated with higher mortality (7.1 vs. 4.3%; odds ratio 1.09; 95% confidence interval [CI] 1.07–1.12, p 
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2024.132111