RIFM fragrance ingredient safety assessment, 2H-1,5-benzodioxepin-3(4H)-one, 7-(1-methylethyl)-, CAS Registry Number 950919-28-5

•2H-1,5-Benzodioxepin-3(4H)-one, 7-(1-methylethyl)-; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were cleared using target data, read-across, and/or TTC.

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Bibliographic Details
Published in:Food and chemical toxicology 2024-07, Vol.189, p.114703-114703, Article 114703
Main Authors: Api, A.M., Bartlett, A., Belsito, D., Botelho, D., Bruze, M., Bryant-Freidrich, A., Burton, G.A., Cancellieri, M.A., Chon, H., Dagli, M.L., Dekant, W., Deodhar, C., Farrell, K., Fryer, A.D., Jones, L., Joshi, K., Lapczynski, A., Lavelle, M., Lee, I., Moustakas, H., Muldoon, J., Penning, T.M., Ritacco, G., Sadekar, N., Schember, I., Schultz, T.W., Siddiqi, F., Sipes, I.G., Sullivan, G., Thakkar, Y., Tokura, Y.
Format: Article
Language:English
Subjects:
Animals
Consumer Product Safety
Endpoint Determination
Humans
No-Observed-Adverse-Effect Level
Odorants
Perfume - chemistry
Perfume - toxicity
Risk Assessment
Toxicity Tests
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Description
Summary:•2H-1,5-Benzodioxepin-3(4H)-one, 7-(1-methylethyl)-; a safety assessment based on RIFM's criteria.•A safety assessment based on 7 human health endpoints plus environmental.•All endpoints were cleared using target data, read-across, and/or TTC.
ISSN:0278-6915
1873-6351
DOI:10.1016/j.fct.2024.114703