The Risk of Breast Implant-Associated Anaplastic Large Cell Lymphoma; A Systematic Review and Meta-Analysis

Background Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an emerging disorder that has gained global attention throughout the past era. The present meta-analysis was performed to retrieve the risk of BIA-ALCL from population-based epidemiological studies. Factors associated...

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Bibliographic Details
Published in:Aesthetic plastic surgery 2024-12, Vol.48 (24), p.5315-5328
Main Authors: Elameen, Ali Mohamed, AlMarakby, Mohamed Awad, Atta, Tarek Ibrahim, Dahy, Asmaa Ali
Format: Article
Language:English
Subjects:
Breast cancer
Breast implants
Lymphoma
Medicine
Medicine & Public Health
Meta-analysis
Otorhinolaryngology
Plastic Surgery
Reconstructive surgery
Review
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Summary:Background Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an emerging disorder that has gained global attention throughout the past era. The present meta-analysis was performed to retrieve the risk of BIA-ALCL from population-based epidemiological studies. Factors associated with BIA-ALCL were evaluated to identify patients at higher risk of BIA-ALCL. Methods A systematic literature search was executed throughout 12 databases. All epidemiological studies encompassing patients with breast implants either for aesthetic or reconstructive purposes and reported the risk of BIA-ALCL were included. Studies reported the risk factors of BIA-ALCL were included. Results The present meta-analysis included 17 articles, encompassing 525,475 patients with breast implants. There were 254 patients with BIA-ALCL with a mean duration to the diagnosis of BIA-ALCL of 13.16 years (95% CI 11.7–14.6, P  
ISSN:0364-216X
1432-5241
1432-5241
DOI:10.1007/s00266-024-03956-9