Vitamin D and Albumin Deficiency in a Swiss Orthopaedic Surgery In-Patient Cohort

• Published in: Journal of clinical medicine 2024-05, Vol.13 (9), p.2577
• Main Authors: Kingston, Craig David, Santini, Simone, Hauke, Dorian, Valderrabano, Victor
• Format: Article
• Language: English
• Subjects: Albumin; Alfacalcidol; Anemia; Calcifediol; Complications and side effects; Demographic aspects; Diagnosis; Elective surgery; Health aspects; Hemoglobin; Malnutrition; Measurement; Mortality; Orthopedic surgery; Orthopedics; Patient outcomes; Patients; Proteins; Serology; Serum albumin; Surgical outcomes; Type 2 diabetes; Vitamin D; Vitamin D deficiency; Vitamin deficiency; Womens health
• ISSN: 2077-0383; 2077-0383
• DOI: 10.3390/jcm13092577

Vitamin D and protein deficiencies are common conditions in the general population. In Orthopaedic surgery, they can result in wound complications or poor bone healing. The goal of this study was, therefore, to determine the prevalence of vitamin D and albumin deficiencies in patients scheduled for elective Orthopaedic procedures. We performed an observational, noninterventional study using the demographic characteristics via means chart analysis of in-patients with an elective surgery in a single Swiss Orthopaedic centre. The following variables were collected and analysed: age, gender, BMI, ASA score, rate of vitamin D supplementation before surgery, and serum preoperative levels of vitamin D, albumin, Haemoglobin, calcium, and phosphate. A total of 336 patients were analysed; there were 218 women (64.9%) and 118 men (35.1%). The average age was 59.4 years (17-89 years). The average BMI was 26.8 kg/m (17.8-37.6) and the average ASA score was II (I-III). The overall prevalence of vitamin D deficiency was 82.1%, being more common in the male (89.8%) than female patients (77.9%). Patients who received vitamin D supplements before surgery had an average vitamin D level in the normal range. Of the subgroup of 170 patients who were over 60 years of age, 78.8% of the patients were Vitamin D deficient, with deficiency once again being more common in men (93.3%) than in women (92%). Albumin deficiency was documented in 58.9% of the cases. A total of 62.8% of all the female patients were albumin deficient, and 51.7% of all male patients were. Of the subgroup of 170 patients who were over 60 years of age, 71.8% of the patients were albumin deficient, with the deficiency being practically identical in men (71.1%) and women (72%). Despite increased awareness in the medical community, vitamin D and albumin deficiencies remain highly prevalent in elective Orthopaedic patients. Pre/perioperative screening and addressing possible vitamin D and albumin deficiencies are of great importance for good outcomes in Orthopaedic surgery.