Embryo development and live birth in women with one previously failed full IVF/ICSI cycle

Purpose To evaluate the embryological and pregnancy outcomes of women who failed in their first IVF treatment if they attempted a second cycle. Methods For evaluating the embryological outcomes, the study cohort included 1,227 women who failed to obtain a live birth after the initial IVF cycle from...

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Bibliographic Details
Published in:Journal of assisted reproduction and genetics 2024-06, Vol.41 (6), p.1517-1525
Main Authors: Wen, Wen, Zhang, Dian, Liu, Xiaohua, Shi, Juanzi, Cai, He
Format: Article
Language:English
Subjects:
Adult
Assisted Reproduction Technologies
Birth
Birth Rate
Blastocyst - physiology
Blastocysts
Embryo Culture Techniques - methods
Embryo Implantation
Embryo Transfer - methods
Embryonic Development
Embryos
Female
Fertilization in Vitro - methods
Gynecology
Human Genetics
Humans
Implantation
In vitro fertilization
Live Birth - epidemiology
Medicine
Medicine & Public Health
Oocyte Retrieval - methods
Oocytes
Oocytes - growth & development
Pregnancy
Pregnancy Outcome
Pregnancy Rate
Reproductive Medicine
Sperm Injections, Intracytoplasmic - methods
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Summary:Purpose To evaluate the embryological and pregnancy outcomes of women who failed in their first IVF treatment if they attempted a second cycle. Methods For evaluating the embryological outcomes, the study cohort included 1,227 women who failed to obtain a live birth after the initial IVF cycle from September 2018 to August 2021 and returned for a second attempt. To evaluate reproductive outcomes including live birth rates (LBRs), 1227 women who returned for a second attempt were compared with 13,195 women undergoing their first oocyte retrieval with blastocyst culture attempted during the same study period. Results In women who had a second cycle, the median number of oocyte retrieved (11 vs 9), fertilized oocytes (7 vs 5), usable embryos (6 vs 4) and blastocysts (3 vs 1) was higher in the second cycle compared to the first cycle (All p  
ISSN:1058-0468
1573-7330
1573-7330
DOI:10.1007/s10815-024-03107-8