GLP‐1 agonists and hair loss: a call for further investigation

The widespread adoption of glucagon‐like peptide‐1 (GLP‐1) agonists in treating type 2 diabetes mellitus (T2DM) and obesity has sparked investigations into their impact on hair health, an area characterized by diverse conjectures. Some propose potential risks such as disrupted hair growth cycles or...

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Bibliographic Details
Published in:International journal of dermatology 2024-09, Vol.63 (9), p.1128-1130
Main Authors: Desai, Deesha D., Sikora, Michelle, Nohria, Ambika, Bordone, Lindsey, Caplan, Avrom S., Shapiro, Jerry, Lo Sicco, Kristen I.
Format: Article
Language:English
Subjects:
Agonists
Alopecia
Alopecia - drug therapy
Blood circulation
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Diabetes Mellitus, Type 2 - drug therapy
Glucagon
Glucagon-Like Peptide 1 - agonists
glucagon‐like peptide‐1
Hair
Hair - drug effects
Hair - growth & development
Humans
Hypoglycemic Agents - adverse effects
Hypoglycemic Agents - therapeutic use
Insulin Resistance
microvasculature
Obesity - drug therapy
Scalp
telogen effluvium
type 2 diabetes mellitus
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Summary:The widespread adoption of glucagon‐like peptide‐1 (GLP‐1) agonists in treating type 2 diabetes mellitus (T2DM) and obesity has sparked investigations into their impact on hair health, an area characterized by diverse conjectures. Some propose potential risks such as disrupted hair growth cycles or premature androgenetic alopecia (AGA), while others suggest benefits linked to improved insulin sensitivity and enhanced scalp blood circulation. However, despite these theoretical underpinnings, clinical evidence linking GLP‐1 agonists to hair loss remains sparse. The necessity for vigilant patient monitoring and collaborative efforts cannot be overstressed in comprehensively addressing any potential consequences of GLP‐1 agonist therapy on hair health as their use continues to expand.
ISSN:0011-9059
1365-4632
1365-4632
DOI:10.1111/ijd.17246