Effects of Passiflora incarnata and Valeriana officinalis in the control of anxiety due to tooth extraction: a randomized controlled clinical trial

Objective This study evaluated the efficacy of Valeriana officinalis L. and Passiflora incarnata L. to control anxiety, surgical discomfort, and changes in vital signs of patients undergoing extraction of two unilateral third molars. Materials and methods This study is a randomized, triple-blinded c...

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Published in:Oral and maxillofacial surgery 2024-09, Vol.28 (3), p.1313-1320
Main Authors: Velasquez, Amalia Celsy Abregu, Tsuji, Mayumi, dos Santos Cordeiro, Lidiana, Petinati, Maria Fernanda Pivetta, Rebellato, Nelson Luis Barbosa, Sebastiani, Aline Monise, da Costa, Delson João, Scariot, Rafaela
Format: Article
Language:English
Subjects:
Adult
Anxiety
Clinical trials
Dental Anxiety - prevention & control
Female
Humans
Male
Medicine
Medicine & Public Health
Molar, Third - surgery
Oral and Maxillofacial Surgery
Passiflora
Phytotherapy
Plant Extracts - therapeutic use
Tooth Extraction
Tooth extractions
Valerian
Young Adult
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Summary:Objective This study evaluated the efficacy of Valeriana officinalis L. and Passiflora incarnata L. to control anxiety, surgical discomfort, and changes in vital signs of patients undergoing extraction of two unilateral third molars. Materials and methods This study is a randomized, triple-blinded clinical trial. Fifty-four patients were allocated into three groups (Valeriana officinalis L., Passiflora incarnata L., and placebo). Anxiety levels were assessed using the State-Trace Anxiety Inventory (STAI) index, surgical discomfort using the QCirDental, and through the measurement of vital signs. The surgical times evaluated were before (T0), during (T1), and after surgery (T2). Results There was evidence that both Valeriana officinalis L. and Passiflora incarnata L., reduced STAY-S scores between T0 and T2 ( p  
ISSN:1865-1569
1865-1550
1865-1569
DOI:10.1007/s10006-024-01259-6